Technology Process of <1R-(1α,2β,5β,6β)>-<5,6-di(benzoyloxy)-2-methoxy-3-cyclohexen-1-yl> (l)-menthoxyacetate
There total 6 articles about <1R-(1α,2β,5β,6β)>-<5,6-di(benzoyloxy)-2-methoxy-3-cyclohexen-1-yl> (l)-menthoxyacetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 84 percent / DMAP / pyridine / 1.) 0 deg C, 2.5 h, 2.) RT
2: 73 percent / m-CPBA / CH2Cl2 / 22 h / Ambient temperature; pH 8 phosphate buffer
3: 100 percent / camphorsulfonic acid monohydrate / CHCl3 / 22.5 h / Ambient temperature
4: MAP / pyridine; CH2Cl2 / 48 h / Ambient temperature
With
dmap; Medroxyprogesterone acetate; camphor-10-sulfonic acid; 3-chloro-benzenecarboperoxoic acid;
In
pyridine; dichloromethane; chloroform;
DOI:10.1016/S0040-4020(01)81025-5
- Guidance literature:
-
Multi-step reaction with 2 steps
1: oxalyl chloride, DMF / CH2Cl2 / 3.5 h / Ambient temperature
2: MAP / pyridine; CH2Cl2 / 48 h / Ambient temperature
With
oxalyl dichloride; Medroxyprogesterone acetate; N,N-dimethyl-formamide;
In
pyridine; dichloromethane;
DOI:10.1016/S0040-4020(01)81025-5
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 73 percent / m-CPBA / CH2Cl2 / 22 h / Ambient temperature; pH 8 phosphate buffer
2: 100 percent / camphorsulfonic acid monohydrate / CHCl3 / 22.5 h / Ambient temperature
3: MAP / pyridine; CH2Cl2 / 48 h / Ambient temperature
With
Medroxyprogesterone acetate; camphor-10-sulfonic acid; 3-chloro-benzenecarboperoxoic acid;
In
pyridine; dichloromethane; chloroform;
DOI:10.1016/S0040-4020(01)81025-5
