5-Benzyloxy-3-(4-hydroxymethylphenoxy)-4-methoxybenzylalkohol

Base Information

• Chemical Name: 5-Benzyloxy-3-(4-hydroxymethylphenoxy)-4-methoxybenzylalkohol
• CAS No.: 118799-08-9
• Molecular Formula: C₂₂H₂₂O₅
• Molecular Weight: 366.414
• Mol file: 118799-08-9.mol

Synonyms:5-Benzyloxy-3-(4-hydroxymethylphenoxy)-4-methoxybenzylalkohol

Chemical Property of 5-Benzyloxy-3-(4-hydroxymethylphenoxy)-4-methoxybenzylalkohol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Benzyloxy-3-(4-hydroxymethylphenoxy)-4-methoxybenzylalkohol

There total 9 articles about 5-Benzyloxy-3-(4-hydroxymethylphenoxy)-4-methoxybenzylalkohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

5-Benzyloxy-4-methoxy-3-<4-(methoxycarbonyl)phenoxy>benzoesaeure-methylester (118799-07-8) → 5-Benzyloxy-3-(4-hydroxymethylphenoxy)-4-methoxybenzylalkohol (118799-08-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran;

Reference yield:

4-methoxycarbonylphenyl bromide (619-42-1) → 5-Benzyloxy-3-(4-hydroxymethylphenoxy)-4-methoxybenzylalkohol (118799-08-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 37 percent / K₂CO₃; CuO / pyridine / 48 h / 120 °C

2: 76 percent / K₂CO₃ / acetone / 5 h / Heating

3: 91 percent / LiAlH₄ / tetrahydrofuran

With lithium aluminium tetrahydride; potassium carbonate; copper(II) oxide; In tetrahydrofuran; pyridine; acetone;

Reference yield:

methyl 3,5-dihydroxy-4-methoxybenzoate (24093-81-0) → 5-Benzyloxy-3-(4-hydroxymethylphenoxy)-4-methoxybenzylalkohol (118799-08-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 37 percent / K₂CO₃; CuO / pyridine / 48 h / 120 °C

2: 76 percent / K₂CO₃ / acetone / 5 h / Heating

3: 91 percent / LiAlH₄ / tetrahydrofuran

With lithium aluminium tetrahydride; potassium carbonate; copper(II) oxide; In tetrahydrofuran; pyridine; acetone;

upstream raw materials:

3-Benzyloxy-2-methoxydiphenylether-4',5-dicarbonsaeurediethylester

5-Benzyloxy-4-methoxy-3-<4-(methoxycarbonyl)phenoxy>benzoesaeure-methylester

4-methoxycarbonylphenyl bromide

methyl 3,5-dihydroxy-4-methoxybenzoate

Downstream raw materials:

5-Benzyloxy-3-(4-brommethylphenoxy)-4-methoxybenzylbromid

<5-Benzyloxy-4-methoxy-2-<4-(triphenylphosphoniomethyl)phenoxy>benzyl>phosphonium-dibromid

perrottetin G

3-Benzyloxy-5-<(3-benzyloxyphenyl)ethenyl>-1-<4-<2-(3-benzyloxyphenyl)ethenyl>phenoxy>-2-methoxybenzol