C₂₀H₁₄ClN₃O

Base Information

• Chemical Name: C₂₀H₁₄ClN₃O
• CAS No.: 1440142-00-6
• Molecular Formula: C₂₀H₁₄ClN₃O
• Molecular Weight: 347.804
• Mol file: 1440142-00-6.mol

Synonyms:C₂₀H₁₄ClN₃O

Chemical Property of C₂₀H₁₄ClN₃O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₁₄ClN₃O

There total 4 articles about C₂₀H₁₄ClN₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.3%

2-phenyl-1H-benzo[d]imidazol-5-amine (1767-25-5) + 4-chloro-benzoyl chloride (122-01-0) → C20H14ClN3O (1440142-00-6)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 5h;

DOI:10.2174/157340613804488440

Reference yield:

benzaldehyde (100-52-7) → C20H14ClN3O (1440142-00-6)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium metabisulfite / ethanol; water / Cooling

2: N,N-dimethyl-formamide / 4 h / 130 °C

3: stannous chloride dihydrate / ethanol / 4 h / 70 °C

4: triethylamine / tetrahydrofuran / 5 h / 20 °C

With stannous chloride dihydrate; sodium metabisulfite; triethylamine; In tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide;

DOI:10.2174/157340613804488440

Reference yield:

sodium hydroxy(phenyl)methanesulfonate (4657-12-9) → C20H14ClN3O (1440142-00-6)

Guidance literature:

Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide / 4 h / 130 °C

2: stannous chloride dihydrate / ethanol / 4 h / 70 °C

3: triethylamine / tetrahydrofuran / 5 h / 20 °C

With stannous chloride dihydrate; triethylamine; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;

DOI:10.2174/157340613804488440

upstream raw materials:

2-phenyl-1H-benzo[d]imidazol-5-amine

4-chloro-benzoyl chloride

benzaldehyde

sodium hydroxy(phenyl)methanesulfonate