Technology Process of C53H66F3NO9
There total 3 articles about C53H66F3NO9 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
phenyl 4,6-O-benzylidene-2-O-[3-(4-trifluoromethylphenyl)-prop-2-ynyl]-3-O-benzyl-1-thio-α-D-mannopyranoside;
With
1-benzenesulfinyl piperidine; trifluoromethylsulfonic anhydride; 2,4,6-tri-tert-butylpyrimidine;
In
dichloromethane;
at -60 ℃;
for 0.5h;
Inert atmosphere;
Molecular sieve;
C23H41NO4;
In
dichloromethane;
at -60 ℃;
for 21h;
optical yield given as %de;
diastereoselective reaction;
Inert atmosphere;
DOI:10.1002/anie.201006230
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: titanium tetrachloride / dichloromethane / -78 - -40 °C / Inert atmosphere
1.2: 20 °C / Saturated solution
2.1: 1-benzenesulfinyl piperidine; trifluoromethylsulfonic anhydride; 2,4,6-tri-tert-butylpyrimidine / dichloromethane / 0.5 h / -60 °C / Inert atmosphere; Molecular sieve
2.2: 21 h / -60 °C / Inert atmosphere
With
1-benzenesulfinyl piperidine; trifluoromethylsulfonic anhydride; titanium tetrachloride; 2,4,6-tri-tert-butylpyrimidine;
In
dichloromethane;
1.1: Mukaiyama reaction;
DOI:10.1002/anie.201006230
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: titanium tetrachloride / dichloromethane / -78 - -40 °C / Inert atmosphere
1.2: 20 °C / Saturated solution
2.1: 1-benzenesulfinyl piperidine; trifluoromethylsulfonic anhydride; 2,4,6-tri-tert-butylpyrimidine / dichloromethane / 0.5 h / -60 °C / Inert atmosphere; Molecular sieve
2.2: 21 h / -60 °C / Inert atmosphere
With
1-benzenesulfinyl piperidine; trifluoromethylsulfonic anhydride; titanium tetrachloride; 2,4,6-tri-tert-butylpyrimidine;
In
dichloromethane;
1.1: Mukaiyama reaction;
DOI:10.1002/anie.201006230
![phenyl 4,6-O-benzylidene-2-O-[3-(4-trifluoromethylphenyl)-prop-2-ynyl]-3-O-benzyl-1-thio-α-D-mannopyranoside](/Databaselist/images/loading.webp)
