α-bromo-4-fluoro-3-methylphenylglyoxal benzimidazol-2-ylhydrazone

Base Information

• Chemical Name: α-bromo-4-fluoro-3-methylphenylglyoxal benzimidazol-2-ylhydrazone
• CAS No.: 132326-48-8
• Molecular Formula: C₁₆H₁₂BrFN₄O
• Molecular Weight: 375.2
• Mol file: 132326-48-8.mol

Synonyms:α-bromo-4-fluoro-3-methylphenylglyoxal benzimidazol-2-ylhydrazone

Chemical Property of α-bromo-4-fluoro-3-methylphenylglyoxal benzimidazol-2-ylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-bromo-4-fluoro-3-methylphenylglyoxal benzimidazol-2-ylhydrazone

There total 3 articles about α-bromo-4-fluoro-3-methylphenylglyoxal benzimidazol-2-ylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

4-fluoro-3-methylphenylglyoxal benzimidazol-2-ylhydrazone (132326-44-4) → α-bromo-4-fluoro-3-methylphenylglyoxal benzimidazol-2-ylhydrazone (132326-48-8)

Guidance literature:

With N-Bromosuccinimide; In tetrachloromethane; for 3h; Heating;

Reference yield:

2-hydrazinobenzimidazole (15108-18-6) → α-bromo-4-fluoro-3-methylphenylglyoxal benzimidazol-2-ylhydrazone (132326-48-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / ethanol / 5 h / Heating

2: 89 percent / N-bromosuccinimide / CCl₄ / 3 h / Heating

With N-Bromosuccinimide; In tetrachloromethane; ethanol;

Reference yield:

4-fluoro-3-methylphenylglyoxal (81593-26-2) → α-bromo-4-fluoro-3-methylphenylglyoxal benzimidazol-2-ylhydrazone (132326-48-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / ethanol / 5 h / Heating

2: 89 percent / N-bromosuccinimide / CCl₄ / 3 h / Heating

With N-Bromosuccinimide; In tetrachloromethane; ethanol;

upstream raw materials:

4-fluoro-3-methylphenylglyoxal benzimidazol-2-ylhydrazone

2-hydrazinobenzimidazole

4-fluoro-3-methylphenylglyoxal

Downstream raw materials:

5-(1H-Benzoimidazol-2-ylazo)-4-(4-fluoro-3-methyl-phenyl)-thiazol-2-ylamine