C₂₂H₂₈O₃Si

Base Information

• Chemical Name: C₂₂H₂₈O₃Si
• CAS No.: 1305339-37-0
• Molecular Formula: C₂₂H₂₈O₃Si
• Molecular Weight: 368.548
• Mol file: 1305339-37-0.mol

Synonyms:C₂₂H₂₈O₃Si

Chemical Property of C₂₂H₂₈O₃Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₈O₃Si

There total 2 articles about C₂₂H₂₈O₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

C22H26OSi (1305339-36-9) → C22H28O3Si (1305339-37-0)

Guidance literature:

With methanesulfonamide; AD-mix β; In water; tert-butyl alcohol; at 0 ℃; for 48h; optical yield given as %ee; enantioselective reaction;

DOI:10.1016/j.tetlet.2010.10.141

Reference yield:

tert-butyl(diphenyl)(2-propynyloxy)silane (88159-06-2) → C22H28O3Si (1305339-37-0)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / pyrrolidine / 3 h / 20 °C

2: AD-mix β; methanesulfonamide / water; tert-butyl alcohol / 48 h / 0 °C

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; methanesulfonamide; AD-mix β; In pyrrolidine; water; tert-butyl alcohol; 1: Sonogashira coupling / 2: Sharpless asymmetric dihydroxylation;

DOI:10.1016/j.tetlet.2010.10.141

Reference yield: 96.0%

C22H28O3Si (1305339-37-0) + 2,2-dimethoxy-propane (77-76-9) → C25H32O3Si (1305339-35-8)

Guidance literature:

With pyridinium p-toluenesulfonate; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1016/j.tetlet.2010.10.141

upstream raw materials:

C₂₂H₂₆OSi

tert-butyl(diphenyl)(2-propynyloxy)silane

Downstream raw materials:

C₂₅H₃₂O₃Si