2-(4-Chlorophenyl)-2-fluoroacetonitrile

Base Information

Chemical Name:2-(4-Chlorophenyl)-2-fluoroacetonitrile
CAS No.:106468-05-7
Molecular Formula:C₈H₅ClFN
Molecular Weight:169.586
Hs Code.:
European Community (EC) Number:859-952-8
Nikkaji Number:J2.839.600G

Synonyms:2-(4-chlorophenyl)-2-fluoroacetonitrile;106468-05-7;SCHEMBL444030;Fluoro 4-chlorophenylacetonitrile;EN300-195183

Suppliers and Price of 2-(4-Chlorophenyl)-2-fluoroacetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Chlorophenyl)-2-fluoroacetonitrile
100mg
$ 285.00

TRC
2-(4-Chlorophenyl)-2-fluoroacetonitrile
50mg
$ 200.00

TRC
2-(4-Chlorophenyl)-2-fluoroacetonitrile
10mg
$ 45.00

AK Scientific
2-(4-Chlorophenyl)-2-fluoroacetonitrile
1g
$ 870.00

AK Scientific
2-(4-Chlorophenyl)-2-fluoroacetonitrile
500mg
$ 700.00

Total 2 raw suppliers

Chemical Property of 2-(4-Chlorophenyl)-2-fluoroacetonitrile

Chemical Property:

Boiling Point:239.5±25.0 °C(Predicted)
Density:1.267±0.06 g/cm3(Predicted)
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:169.0094550
Heavy Atom Count:11
Complexity:166

Purity/Quality:

95% ^*data from raw suppliers

2-(4-Chlorophenyl)-2-fluoroacetonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C(C#N)F)Cl

Technology Process of 2-(4-Chlorophenyl)-2-fluoroacetonitrile

There total 5 articles about 2-(4-Chlorophenyl)-2-fluoroacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

: 140-53-4
p-chlorobenzyl cyanide

: 106468-05-7
α-fluoro(p-chlorophenyl)acetonitrile

: 104-88-1
4-chlorobenzaldehyde

Guidance literature:: With tetrabutylammonium tetrafluoroborate; triethylamine tris(hydrogen fluoride); In acetonitrile; at 13 ℃; anodic oxidation;
DOI:10.1016/S0040-4020(01)89079-7

Reference yield:

: 66985-46-4
(+/-)-2-(4-chlorophenyl)-2-(trimethylsiloxy)-acetonitrile

: 106468-05-7
α-fluoro(p-chlorophenyl)acetonitrile

Guidance literature:: With diethylamino-sulfur trifluoride; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;
DOI:10.2174/157017861203150303114411

Reference yield:

: 7677-24-9
trimethylsilyl cyanide

: 104-88-1
4-chlorobenzaldehyde

: 106468-05-7
α-fluoro(p-chlorophenyl)acetonitrile

Guidance literature:: With diethylamino-sulfur trifluoride; zinc(II) iodide; Multistep reaction; 1.) CH₂Cl₂, 30 deg C, 1 h, 2.) CH₂Cl₂, reflux, 3 h;
DOI:10.1248/cpb.43.1668