umuhengerin

Base Information

• Chemical Name: umuhengerin
• CAS No.: 29215-55-2
• Molecular Formula: C20H20 O8
• Molecular Weight: 388.374
• Hs Code.: 2914509090
• Mol file: 29215-55-2.mol

Synonyms:Flavone,5-hydroxy-3',4',5',6,7-pentamethoxy- (8CI); 5-Hydroxy-3',4',5',6,7-pentamethoxyflavone;5-Hydroxy-6,7,3',4',5'-pentamethoxyflavone; Umuhengerin

Chemical Property of umuhengerin

Chemical Property:

• Vapor Pressure: 4.18E-14mmHg at 25°C
• Boiling Point: 581.2°Cat760mmHg
• Flash Point: 205.9°C
• PSA: 96.59000
• Density: 1.304g/cm³
• LogP: 3.20860

Purity/Quality:

96% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of umuhengerin

There total 6 articles about umuhengerin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3',4',5,5',6,7-Hexamethoxyflavone (29043-07-0) → 5-hydroxyl-6,7,3′,4′,5′-pentamethoxyflavone (29215-55-2)

Guidance literature:

3',4',5,5',6,7-Hexamethoxyflavone; With aluminum (III) chloride; In acetonitrile; for 1h; Heating;

With hydrogenchloride; In water; for 1h; regioselective reaction; Reflux;

DOI:10.1080/14786419.2021.1961136

Reference yield:

3,4,5-trimethoxy-benzaldehyde (86-81-7) → 5-hydroxyl-6,7,3′,4′,5′-pentamethoxyflavone (29215-55-2)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C

1.2: 3 h / 20 °C

2.1: sodium acetate / 110 °C

2.2: 18 h / 110 °C

3.1: potassium hydroxide / water / 56 h

4.1: sulfuric acid / dimethyl sulfoxide / Heating

5.1: aluminum (III) chloride / acetonitrile / 1 h / Heating

5.2: 1 h / Reflux

With aluminum (III) chloride; sulfuric acid; sodium acetate; 3-chloro-benzenecarboperoxoic acid; potassium hydroxide; In dichloromethane; water; dimethyl sulfoxide; acetonitrile; 1.1: |Baeyer-Villiger Ketone Oxidation / 2.2: |Fries Phenol Ester Rearrangement / 3.1: |Claisen-Schmidt Condensation;

DOI:10.1080/14786419.2021.1961136

Reference yield:

3,4,5-trimethoxyphenol (642-71-7) → 5-hydroxyl-6,7,3′,4′,5′-pentamethoxyflavone (29215-55-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium acetate / 110 °C

1.2: 18 h / 110 °C

2.1: potassium hydroxide / water / 56 h

3.1: sulfuric acid / dimethyl sulfoxide / Heating

4.1: aluminum (III) chloride / acetonitrile / 1 h / Heating

4.2: 1 h / Reflux

With aluminum (III) chloride; sulfuric acid; sodium acetate; potassium hydroxide; In water; dimethyl sulfoxide; acetonitrile; 1.2: |Fries Phenol Ester Rearrangement / 2.1: |Claisen-Schmidt Condensation;

DOI:10.1080/14786419.2021.1961136

upstream raw materials:

3',4',5',5,6,7-hexahydroxyflavone

acetone

dimethyl sulfate

3',4',5,5',6,7-Hexamethoxyflavone

Downstream raw materials:

3',4',5,5',6,7-Hexamethoxyflavone