Succisulfone

Base Information

• Chemical Name: Succisulfone
• CAS No.: 5934-14-5
• Molecular Formula: C16H16 N2 O5 S
• Molecular Weight: 348.379
• European Community (EC) Number: 227-684-5
• UNII: 0Z4EEC962O
• DSSTox Substance ID: DTXSID00863657
• Nikkaji Number: J8.308I
• Wikidata: Q27251064
• NCI Thesaurus Code: C72642
• Metabolomics Workbench ID: 155787
• ChEMBL ID: CHEMBL2105506
• Mol file: 5934-14-5.mol

Synonyms:Succisulfone;5934-14-5;Exosulfonyl;4-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoic acid;Succinylsulfone;Succisulfona;Succisulfonum;4'-Sulfanilylsuccinalic acid;Succisulphone;F 1500;Succisulfone [INN:DCF];4-[4-(4-aminophenyl)sulfonylanilino]-4-oxobutanoic acid;C16H16N2O5S;EINECS 227-684-5;BRN 3458725;UNII-0Z4EEC962O;4'-Sulfanilylsuccinanilic acid;0Z4EEC962O;N-(4-Aminophenylsulfonylphenyl)succinamidsaeure;Succinalic acid, 4'-sulfanilyl-;4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid;Butanoic acid, 4-((4-((4-aminophenyl)sulfonyl)phenyl)amino)-4-oxo-;F-1500;4-13-00-01370 (Beilstein Handbook Reference);4-((4-((4-Aminophenyl)sulphonyl)phenyl)amino)-4-oxobutyric acid;4-[[4-[(4-AMINOPHENYL)SULFONYL]PHENYL]AMINO]-4-OXOBUTYRIC ACID;Succisulfon;4-[[4-[(4-Aminophenyl)sulfonyl]phenyl]amino]-4-oxobutanoic acid;Butanoic acid, 4-[[4-[(4-aminophenyl)sulfonyl]phenyl]amino]-4-oxo-;SUCCINYLDAPSONE;Succisulfone [DCF:INN];SUCCISULFONE [MI];SUCCISULFONE [INN];SUCCISULFONE [MART.];SCHEMBL153245;CHEMBL2105506;DTXSID00863657;CHEBI:135473;Succinanilic acid, 4'-sulfanilyl-;MFCD00864826;HY-W107466;BS-52198;LS-147272;CS-0161025;C75771;A914306;(S)-(+)-1-(alpha-Aminobenzyl)-2-naphtholtartarate;N-[4-(4-Amino-phenylsulfon)-phenyl]-succinamidsaeure;Q27251064;4-[4-(4-aminophenyl)sulfonylanilino]-4-oxo-butanoic acid;4-[4-(4-Aminobenzene-1-sulfonyl)anilino]-4-oxobutanoic acid;3-(N-{4-[(4-Aminophenyl)sulfonyl]phenyl}carbamoyl)propanoic acid;4-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoicacid

Chemical Property of Succisulfone

Chemical Property:

• Melting Point: 157°
• Boiling Point: 706.1±55.0 °C(Predicted)
• PKA: 4.55±0.10(Predicted)
• PSA: 134.94000
• Density: 1.446±0.06 g/cm3(Predicted)
• LogP: 3.63990
• Storage Temp.: 2-8°C(protect from light)
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 348.07799279
• Heavy Atom Count: 24
• Complexity: 541

Purity/Quality:

97% ^*data from raw suppliers

SUCCISULFONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)NC(=O)CCC(=O)O

Technology Process of Succisulfone

There total 5 articles about Succisulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

succinic acid anhydride (108-30-5) + dapsone (80-08-0) → dapsone hapten (5934-14-5)

Guidance literature:

With 1,4-dioxane;

Reference yield:

N-[4-(4-nitro-benzenesulfonyl)-phenyl]-succinamic acid (412278-29-6) → dapsone hapten (5934-14-5)

Guidance literature:

With ethanol; nickel; Hydrogenation;

DOI:10.1021/ja01186a077

Reference yield:

→ dapsone hapten (5934-14-5)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01186a077

upstream raw materials:

succinic acid anhydride

dapsone

N-[4-(4-nitro-benzenesulfonyl)-phenyl]-maleamic acid

N-[4-(4-nitro-benzenesulfonyl)-phenyl]-succinamic acid