Technology Process of (4S,6R)-4-allyl-2,2-dimethyl-6-[(E)-2-phenylvinyl]-1,3-dioxane
There total 19 articles about (4S,6R)-4-allyl-2,2-dimethyl-6-[(E)-2-phenylvinyl]-1,3-dioxane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridinium p-toluenesulfonate;
In
dichloromethane;
at 0 ℃;
for 0.5h;
Inert atmosphere;
DOI:10.1055/s-0030-1260246
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: diisobutylaluminium hydride / tetrahydrofuran; toluene / 0.5 h / -78 °C / Inert atmosphere
1.2: 2 h / 20 °C
1.3: 20 °C
2.1: pyridinium p-toluenesulfonate / dichloromethane / 5.5 h / 0 °C
With
pyridinium p-toluenesulfonate; diisobutylaluminium hydride;
In
tetrahydrofuran; dichloromethane; toluene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: titanium tetrachloride / dichloromethane / 0.08 h / 0 °C / Inert atmosphere
1.2: 0.5 h
1.3: 1 h / -78 - 0 °C
2.1: diisobutylaluminium hydride / tetrahydrofuran; toluene / 0.5 h / -78 °C / Inert atmosphere
2.2: 2 h / 20 °C
2.3: 20 °C
3.1: pyridinium p-toluenesulfonate / dichloromethane / 5.5 h / 0 °C
With
pyridinium p-toluenesulfonate; titanium tetrachloride; diisobutylaluminium hydride;
In
tetrahydrofuran; dichloromethane; toluene;
