2-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl 4-bromobenzoate

Base Information

Chemical Name:2-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl 4-bromobenzoate
CAS No.:1431463-28-3
Molecular Formula:C₁₈H₁₄BrClN₂O₄
Molecular Weight:437.677
Hs Code.:

Synonyms:2-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl 4-bromobenzoate

Suppliers and Price of 2-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl 4-bromobenzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl 4-bromobenzoate

Chemical Property:

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Technology Process of 2-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl 4-bromobenzoate

There total 2 articles about 2-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl 4-bromobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 900937-58-8
2-oxopropyl 4-bromobenzoate

: 73789-56-7
N-isocyaniminotriphenylphosphorane

: 74-11-3
para-chlorobenzoic acid

: 1431463-28-3
2-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl 4-bromobenzoate

Guidance literature:: In dichloromethane; at 20 ℃; for 1h;
DOI:10.1002/jhet.1012

Reference yield:

: 2532-15-2
sodium 4-bromobenzoate

: 1431463-28-3
2-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl 4-bromobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 21 h / 100 °C

2: dichloromethane / 1 h / 20 °C

In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/jhet.1012