Bemesetron

Base Information

Chemical Name:Bemesetron
CAS No.:40796-97-2
Molecular Formula:C15H17 Cl2 N O2
Molecular Weight:314.211
Hs Code.:2933990090
European Community (EC) Number:637-013-1
UNII:O98T3677PA
DSSTox Substance ID:DTXSID8042632
Nikkaji Number:J1.875.100C,J22.994F
Wikipedia:Bemesetron
Wikidata:Q4885099
NCI Thesaurus Code:C80766
Pharos Ligand ID:B4T3N1G5URCR,B4T81D9AQCR4
ChEMBL ID:CHEMBL1257101,CHEMBL2107804,CHEMBL1365455
Mol file:40796-97-2.mol

Synonyms:1 alphaH,3 alphaH,5 alphaH-tropan-3-yl-3,5-dichlorobenzoate;bemesetron;MDL 72222;MDL 72699;MDL-72222;MDL-72699

Suppliers and Price of Bemesetron

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
MDL 72222
50mg
$ 389.00

TRC
MDL-72222
100mg
$ 185.00

Tocris
MDL72222 ≥99%(HPLC)
50
$ 149.00

DC Chemicals
Bemesetron(MDL72222) >98%
1 g
$ 3200.00

DC Chemicals
Bemesetron(MDL72222) >98%
250 mg
$ 1600.00

ChemScene
Bemesetron >99.0%
10mg
$ 120.00

Biorbyt Ltd
Bemesetron >98%
100 mg
$ 1208.70

Biorbyt Ltd
Bemesetron >98%
250 mg
$ 2395.30

Biorbyt Ltd
Bemesetron >98%
1 g
$ 4766.80

ApexBio Technology
MDL72222
10mg
$ 189.00

Total 10 raw suppliers

Chemical Property of Bemesetron

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:165 °C
Boiling Point:406.507°C at 760 mmHg
PKA:9.89±0.40(Predicted)
Flash Point:199.648°C
PSA：29.54000
Density:1.344g/cm³
LogP:3.71330
Storage Temp.:Store at RT
Solubility.:0.1 M HCl: slightly soluble
Water Solubility.:Soluble to 100 mM in DMSO. Insoluble in water. Sparingly soluble in chloroform, and ethanol.
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:313.0636342
Heavy Atom Count:20
Complexity:355

Purity/Quality:

99% ^*data from raw suppliers

MDL 72222 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25
Safety Statements: 36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2CCC1CC(C2)OC(=O)C3=CC(=CC(=C3)Cl)Cl
Isomeric SMILES:CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)C3=CC(=CC(=C3)Cl)Cl
Uses Anti-emetic. It is most often used to study the role of SR-3. Studies suggest the blockade of SR-3 with may ameliorate beta-amyloid protein-induced neurotoxicity by interfering with the increase of Ca2+, and then by inhibiting glutamate release, generation of reactive oxygen species and caspase-3 activity. It is also used in the study of dopamine elevation in rats due to cocaine and amphetamine consumption.
Therapeutic Function Serotonin antagonist

Technology Process of Bemesetron

There total 2 articles about Bemesetron which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: