C₂₂H₃₂O₂Si

Base Information

• Chemical Name: C₂₂H₃₂O₂Si
• CAS No.: 1093117-51-1
• Molecular Formula: C₂₂H₃₂O₂Si
• Molecular Weight: 356.58
• Mol file: 1093117-51-1.mol

Synonyms:C₂₂H₃₂O₂Si

Chemical Property of C₂₂H₃₂O₂Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₂₂H₃₂O₂Si

There total 2 articles about C₂₂H₃₂O₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

Diisopropylsilyl dichloride (7751-38-4) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + 3,4-dihydronaphthalene-1(2H)-one (529-34-0) → C22H32O2Si (1093117-51-1)

Guidance literature:

3,4-dihydronaphthalene-1(2H)-one; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h;

Diisopropylsilyl dichloride; In tetrahydrofuran; at -78 ℃; for 0.75h;

cyclohexanone; In tetrahydrofuran; at -78 ℃; for 0.75h;

DOI:10.1021/acs.joc.1c00384

Reference yield: 83.0%

C16H33NOSi (1093117-49-7) + lithium enolate of 1-tetralone (74074-96-7) → C22H32O2Si (1093117-51-1)

Guidance literature:

C₁₆H₃₃NOSi; With Acetyl bromide; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

lithium enolate of 1-tetralone; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1021/ol802516z

Reference yield: 82.0%

C22H32O2Si (1093117-51-1) → (R,S)-2-((R,S)-2-oxocyclohexyl)-3,4-dihydronaphthalen-1(2H)-one

Guidance literature:

With cerium(IV) ammonium nitrate; sodium hydrogencarbonate; dimethyl sulfoxide; In acetonitrile; propiononitrile; at -10 ℃; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/ol802516z

upstream raw materials:

C₁₆H₃₃NOSi

lithium enolate of 1-tetralone

Diisopropylsilyl dichloride

cyclohexanone