ethyl 3-(4-oxo-1-(2-phenylethyl)-3-piperidinyl)propionate hydrochloride

Base Information

Chemical Name:ethyl 3-(4-oxo-1-(2-phenylethyl)-3-piperidinyl)propionate hydrochloride
CAS No.:130820-32-5
Molecular Formula:C₁₈H₂₅NO₃*ClH
Molecular Weight:339.862
Hs Code.:

Synonyms:ethyl 3-(4-oxo-1-(2-phenylethyl)-3-piperidinyl)propionate hydrochloride

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Chemical Property of ethyl 3-(4-oxo-1-(2-phenylethyl)-3-piperidinyl)propionate hydrochloride

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Technology Process of ethyl 3-(4-oxo-1-(2-phenylethyl)-3-piperidinyl)propionate hydrochloride

There total 3 articles about ethyl 3-(4-oxo-1-(2-phenylethyl)-3-piperidinyl)propionate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 56547-83-2
ethyl 4-oxo-1-(2-phenylethyl)piperidine-3-carboxylate

: 130820-32-5
ethyl 3-(4-oxo-1-(2-phenylethyl)-3-piperidinyl)propionate hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / KOH / dioxane; H₂O / Ambient temperature

2: aq. HCl / 5 h / Heating

3: HCl(gas) / diethyl ether / 4 h / Heating

With hydrogenchloride; potassium hydroxide; In 1,4-dioxane; diethyl ether; water;

Reference yield:

: 72394-38-8
3-(3-ethoxycarbonyl-4-oxo-1-(2-phenylethyl)-3-piperidinyl)propionitrile

: 130820-32-5
ethyl 3-(4-oxo-1-(2-phenylethyl)-3-piperidinyl)propionate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: aq. HCl / 5 h / Heating

2: HCl(gas) / diethyl ether / 4 h / Heating

With hydrogenchloride; In diethyl ether;