8-amino-6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine

Base Information

• Chemical Name: 8-amino-6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine
• CAS No.: 80033-28-9
• Molecular Formula: C₁₉H₁₈FN₅
• Molecular Weight: 335.384

Synonyms:8-amino-6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine

Chemical Property of 8-amino-6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine

Chemical Property:

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Technology Process of 8-amino-6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine

There total 1 articles about 8-amino-6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-(o-fluorophenyl)-1,4,4-trimethyl-8-nitro-4H-s-triazolo[4,3-a][1,4]benzodiazepine (80033-27-8) + tin(IV) chloride (7646-78-8) → 8-amino-6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine (80033-28-9)

Guidance literature:

With sodium hydroxide; In hydrogenchloride; ethanol;

Reference yield:

8-amino-6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine (80033-28-9) → 1-[6-(o-Fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo-[4,3-a][1,4]benzodiazepin-8-yl]-3-(2-hydroxyethyl)urea (80033-30-3)

Guidance literature:

Reference yield:

8-amino-6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine (80033-28-9) → [6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo[4,3-a][1,4]benzodiazepin-8-yl]isocyanate (80033-29-0) + N-[6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo-[4,3-a][1,4]benzodiazepin-8-yl]-1-pyrrolidinecarboxamide (80033-55-2)

Guidance literature:

upstream raw materials:

6-(o-fluorophenyl)-1,4,4-trimethyl-8-nitro-4H-s-triazolo[4,3-a][1,4]benzodiazepine

tin(IV) chloride

Downstream raw materials:

1-[6-(o-Fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo-[4,3-a][1,4]benzodiazepin-8-yl]-3-(2-hydroxyethyl)urea

[6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo[4,3-a][1,4]benzodiazepin-8-yl]isocyanate

N-[6-(o-fluorophenyl)-1,4,4-trimethyl-4H-s-triazolo-[4,3-a][1,4]benzodiazepin-8-yl]-1-pyrrolidinecarboxamide

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