(1S,2R)-1-(benzylamino)-3-(tert-butyldimethylsilyloxy)-1-phenylpropan-2-ol

Base Information

Chemical Name:(1S,2R)-1-(benzylamino)-3-(tert-butyldimethylsilyloxy)-1-phenylpropan-2-ol
CAS No.:1219933-95-5
Molecular Formula:C₂₂H₃₃NO₂Si
Molecular Weight:371.595
Hs Code.:

Synonyms:(1S,2R)-1-(benzylamino)-3-(tert-butyldimethylsilyloxy)-1-phenylpropan-2-ol

Suppliers and Price of (1S,2R)-1-(benzylamino)-3-(tert-butyldimethylsilyloxy)-1-phenylpropan-2-ol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1S,2R)-1-(benzylamino)-3-(tert-butyldimethylsilyloxy)-1-phenylpropan-2-ol

Chemical Property:

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Technology Process of (1S,2R)-1-(benzylamino)-3-(tert-butyldimethylsilyloxy)-1-phenylpropan-2-ol

There total 1 articles about (1S,2R)-1-(benzylamino)-3-(tert-butyldimethylsilyloxy)-1-phenylpropan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 93027-52-2
erythro-3-Benzylamino-3-phenyl-propan-1,2-diol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1219933-95-5
(1S,2R)-1-(benzylamino)-3-(tert-butyldimethylsilyloxy)-1-phenylpropan-2-ol

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 12h; chemoselective reaction; Inert atmosphere;
DOI:10.1016/j.tetasy.2009.12.010

Reference yield: 90.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1219933-95-5
(1S,2R)-1-(benzylamino)-3-(tert-butyldimethylsilyloxy)-1-phenylpropan-2-ol

: 174283-00-2
tert-butyl (1S,2R)-3-(tert-butyldimethylsilyloxy)-2-hydroxy-1-phenylpropylcarbamate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; at 20 ℃; for 12h; under 760.051 Torr;
DOI:10.1016/j.tetasy.2009.12.010