N-benzyl-6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Base Information

Chemical Name:N-benzyl-6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS No.:5417-98-1
Molecular Formula:C13H12 Cl N5
Molecular Weight:273.725
Hs Code.:

Synonyms:1H-Pyrazolo[3,4-d]pyrimidine,4-(benzylamino)-6-chloro-1-methyl- (6CI,8CI); NSC 11636

Suppliers and Price of N-benzyl-6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 6 raw suppliers

Chemical Property of N-benzyl-6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.4g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-benzyl-6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

There total 4 articles about N-benzyl-6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 98141-42-5
4,6-dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

: 100-46-9
benzylamine

: 5417-98-1
N-benzyl-6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 18h;
DOI:10.1021/acs.jmedchem.6b01673

Reference yield: 64.0%

: 5413-84-3
N-benzyl-6-chloro-1H-pyrazolo[3,4-d]pyrimidin-4-amine

: 74-88-4
methyl iodide

: 5417-98-1
N-benzyl-6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

: N-benzyl-6-chloro-2-methyl-2H-pyrazolo[3,4-d]pyrimidin-4-amine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 30 ℃; for 1h;

Reference yield:

: 100-46-9
benzylamine

: 42754-96-1
4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine

: 5417-98-1
N-benzyl-6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

: N-benzyl-6-chloro-2-methyl-2H-pyrazolo[3,4-d]pyrimidin-4-amine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / butan-1-ol / 18 h / 0 - 30 °C

2: potassium carbonate / N,N-dimethyl-formamide / 1 h / 0 - 30 °C

With potassium carbonate; triethylamine; In N,N-dimethyl-formamide; butan-1-ol;