p-tolylidenephthalimidine

Base Information

• Chemical Name: p-tolylidenephthalimidine
• CAS No.: 73502-26-8
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.285
• Mol file: 73502-26-8.mol

Synonyms:p-tolylidenephthalimidine

Chemical Property of p-tolylidenephthalimidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-tolylidenephthalimidine

There total 8 articles about p-tolylidenephthalimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2-Iodobenzoic acid (88-67-5) + 3-(4-methylphenyl)prop-2-ynoic acid (2227-58-9) → (Z)-3-(4-methylbenzylidene)-2,3-dihydro-1H-isoindolin-1-one (73502-26-8)

Guidance literature:

With copper(l) iodide; ammonium acetate; caesium carbonate; In dimethyl sulfoxide; at 120 ℃; for 6h;

DOI:10.1002/adsc.201400451

Reference yield: 67.0%

2-(2-(4-(methyl)phenyl)ethynyl)benzonitrile (253435-24-4) → (Z)-3-(4-methylbenzylidene)-2,3-dihydro-1H-isoindolin-1-one (73502-26-8) + 3-(4-methylphenyl)isoquinoline-1(2H)-one (75040-00-5)

Guidance literature:

With sodium methylate; In tetrahydrofuran; methanol; for 16h; Title compound not separated from byproducts; Heating;

DOI:10.1002/jccs.200100035

Reference yield: 60.0%

3-(4-methylphenyl)prop-2-ynoic acid (2227-58-9) + ortho-chlorobenzoic acid (118-91-2) → p-tolylidenephthalimidine (73502-26-8)

Guidance literature:

With copper(l) iodide; ammonium acetate; potassium carbonate; In 1-methyl-pyrrolidin-2-one; at 135 ℃; for 18h;

DOI:10.1002/bkcs.10348

upstream raw materials:

methanol

2-(2-(4-(methyl)phenyl)ethynyl)benzonitrile

1,2-Diiodobenzene

2-(2-(4-methylphenyl)ethynyl)-1-iodobenzene

Downstream raw materials:

tetra-p-tolyltetrabenzoporphyrin zinc