Technology Process of 1-[(1-methylethoxy)carbonyloxy]methyl 2-[(2,6-dichlorophenyl)amino]phenylacetate
There total 2 articles about 1-[(1-methylethoxy)carbonyloxy]methyl 2-[(2,6-dichlorophenyl)amino]phenylacetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
diclofenac sodium;
With
sodium carbonate;
In
N,N-dimethyl acetamide;
at 30 ℃;
for 0.166667h;
Inert atmosphere;
isopropyloxycarbonyloxymethyl iodide;
In
N,N-dimethyl acetamide;
at -10 ℃;
for 0.75h;
Inert atmosphere;
DOI:10.1021/jm101095e
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium iodide / acetonitrile / 22 h / 30 °C / Inert atmosphere
2.1: sodium carbonate / N,N-dimethyl acetamide / 0.17 h / 30 °C / Inert atmosphere
2.2: 0.75 h / -10 °C / Inert atmosphere
With
sodium carbonate; sodium iodide;
In
N,N-dimethyl acetamide; acetonitrile;
DOI:10.1021/jm101095e
