Celebrex Carboxylic Acid Methyl Ester

Base Information

Chemical Name:Celebrex Carboxylic Acid Methyl Ester
CAS No.:1189893-75-1
Molecular Formula:C₁₈H₁₄F₃N₃O₄S
Molecular Weight:425.388
Hs Code.:
Mol file:1189893-75-1.mol

Synonyms:methyl 4-{1-[4-(aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl}benzoate

Suppliers and Price of Celebrex Carboxylic Acid Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
CelecoxibCarboxylicAcidMethylEster
250mg
$ 1230.00

Medical Isotopes, Inc.
CelebrexCarboxylicAcidMethylEster
25 mg
$ 890.00

American Custom Chemicals Corporation
CELEBREX CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 502.96

Total 5 raw suppliers

Chemical Property of Celebrex Carboxylic Acid Methyl Ester

Chemical Property:

Purity/Quality:

NLT 98% ^*data from raw suppliers

CelecoxibCarboxylicAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Intermediate for the preparation of Celebrex Carboxylic Acid Intermediate for the preparation of Celebrex Carboxylic Acid.

Technology Process of Celebrex Carboxylic Acid Methyl Ester

There total 3 articles about Celebrex Carboxylic Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 67-56-1
methanol

: Carboxy-Celecoxib

: 1189893-75-1
methyl 4-{1-[4-(aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl}benzoate

Guidance literature:: With sulfuric acid; for 1.5h; Reflux; Microwave irradiation;
DOI:10.3184/174751916X14552786665833

Reference yield:

: 169590-42-5,194044-54-7
4-[5-(4-(methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide

: 1189893-75-1
methyl 4-{1-[4-(aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl}benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; potassium permanganate / water / 20 °C

2: sulfuric acid / 1.5 h / Reflux; Microwave irradiation

With potassium permanganate; sulfuric acid; sodium hydroxide; In water;
DOI:10.3184/174751916X14552786665833