N-(2-oxoethyl)-N-(1-phenylvinyl)benzamide

Base Information

• Chemical Name: N-(2-oxoethyl)-N-(1-phenylvinyl)benzamide
• CAS No.: 1426821-25-1
• Molecular Formula: C₁₇H₁₅NO₂
• Molecular Weight: 265.312
• Mol file: 1426821-25-1.mol

Synonyms:N-(2-oxoethyl)-N-(1-phenylvinyl)benzamide

Chemical Property of N-(2-oxoethyl)-N-(1-phenylvinyl)benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of N-(2-oxoethyl)-N-(1-phenylvinyl)benzamide

There total 1 articles about N-(2-oxoethyl)-N-(1-phenylvinyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

4-(N-(4-methoxyphenyl)benzamido)-6-phenylpyridin-3-yl benzoate (1426821-40-0) → N-(2-oxoethyl)-N-(1-phenylvinyl)benzamide (1426821-25-1)

Guidance literature:

4-(N-(4-methoxyphenyl)benzamido)-6-phenylpyridin-3-yl benzoate; With ozone; In methanol; dichloromethane; at -78 ℃; for 2.25h; Inert atmosphere;

With dimethylsulfide; In methanol; dichloromethane; at -78 - 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ja401701x

Reference yield: 92.0%

p-methoxyphenylisonitrile (10349-38-9) + N-(2-oxoethyl)-N-(1-phenylvinyl)benzamide (1426821-25-1) + benzoyl chloride (98-88-4) → 1-benzoyl-4-oxo-6-phenyl-1,2,3,4-tetrahydropyridin-3-yl benzoate

Guidance literature:

p-methoxyphenylisonitrile; N-(2-oxoethyl)-N-(1-phenylvinyl)benzamide; With zinc trifluoromethanesulfonate; at 20 ℃; for 10h; Molecular sieve;

benzoyl chloride; With triethylamine; at 20 ℃; for 0.0833333h;

With hydrogenchloride; at 20 ℃; for 12h;

DOI:10.1039/c4cc10327k

Reference yield: 91.0%

p-methoxyphenylisonitrile (10349-38-9) + N-(2-oxoethyl)-N-(1-phenylvinyl)benzamide (1426821-25-1) + benzoyl chloride (98-88-4) → 4-(N-(4-methoxyphenyl)benzamido)-6-phenylpyridin-3-yl benzoate (1426821-56-8)

Guidance literature:

p-methoxyphenylisonitrile; N-(2-oxoethyl)-N-(1-phenylvinyl)benzamide; With zinc trifluoromethanesulfonate; In acetonitrile; at 20 ℃; Molecular sieve;

benzoyl chloride; With triethylamine; In acetonitrile; for 2h; Solvent; Temperature; Time;

DOI:10.1021/ja401701x

upstream raw materials:

4-(N-(4-methoxyphenyl)benzamido)-6-phenylpyridin-3-yl benzoate

Downstream raw materials:

4-(4-methoxyphenylamino)-6-phenylpyridin-3-yl benzoate

4-(N-(4-methoxyphenyl)benzamido)-6-phenylpyridin-3-yl benzoate

4-(N-(4-methoxyphenyl)acetamido)-6-phenylpyridin-3-yl benzoate

benzoic acid 3-pyridyl ester