Technology Process of methyl 37-(1,2-dithiolan-3-yl)-3-(2-methoxy-2-oxoethyl)-4-(methoxy-carbonyl)-10,33-dioxo-11,14,17,20,23,26,29-heptaoxa-3,9,32-triaza-heptatriacontan-1-oate
There total 1 articles about methyl 37-(1,2-dithiolan-3-yl)-3-(2-methoxy-2-oxoethyl)-4-(methoxy-carbonyl)-10,33-dioxo-11,14,17,20,23,26,29-heptaoxa-3,9,32-triaza-heptatriacontan-1-oate which
guide to synthetic route it.
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synthetic route:
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1292268-32-6
methyl 37-(1,2-dithiolan-3-yl)-3-(2-methoxy-2-oxoethyl)-4-(methoxy-carbonyl)-10,33-dioxo-11,14,17,20,23,26,29-heptaoxa-3,9,32-triaza-heptatriacontan-1-oate
- Guidance literature:
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Multi-step reaction with 7 steps
1.1: ethanol / 0 - 20 °C
2.1: dmap; triethylamine / dichloromethane / 20 °C / Inert atmosphere
3.1: sodium hydroxide / water; toluene / 1 h / 100 °C
3.2: 20 - 100 °C
4.1: dichloromethane / 20 °C / Inert atmosphere
5.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 20 °C
6.1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C / Inert atmosphere
7.1: triethylamine / dichloromethane / 20 °C / pH 8.5
With
dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; trifluoroacetic acid; sodium hydroxide;
In
ethanol; dichloromethane; water; toluene;
DOI:10.1002/ejoc.201001666