N-(4-Amino-2-methoxyphenyl)-4-phenyl-1-piperazineacetamide

Base Information

Chemical Name:N-(4-Amino-2-methoxyphenyl)-4-phenyl-1-piperazineacetamide
CAS No.:110506-40-6
Molecular Formula:C₁₉H₂₄N₄O₂
Molecular Weight:340.425
Hs Code.:
DSSTox Substance ID:DTXSID001192937

Synonyms:DTXSID001192937;N-(4-Amino-2-methoxyphenyl)-4-phenyl-1-piperazineacetamide;110506-40-6

Suppliers and Price of N-(4-Amino-2-methoxyphenyl)-4-phenyl-1-piperazineacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-(4-Amino-2-methoxyphenyl)-4-phenyl-1-piperazineacetamide

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:340.18992602
Heavy Atom Count:25
Complexity:420

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)N)NC(=O)CN2CCN(CC2)C3=CC=CC=C3

Technology Process of N-(4-Amino-2-methoxyphenyl)-4-phenyl-1-piperazineacetamide

There total 4 articles about N-(4-Amino-2-methoxyphenyl)-4-phenyl-1-piperazineacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 110506-21-3
N-(2-Methoxy-4-nitro-phenyl)-2-(4-phenyl-piperazin-1-yl)-acetamide

: 110506-40-6
N-(4-Amino-2-methoxy-phenyl)-2-(4-phenyl-piperazin-1-yl)-acetamide

Guidance literature:: With hydrazine hydrate; nickel; In ethanol; for 2h; Heating;

Reference yield:

: 92-54-6
4-phenyl-1-piperazine

: 110506-40-6
N-(4-Amino-2-methoxy-phenyl)-2-(4-phenyl-piperazin-1-yl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / K₂CO₃ / acetone / 4 h / Heating

2: 73 percent / 100percent N₂H₄*H₂O / Raney nickel / ethanol / 2 h / Heating

With potassium carbonate; hydrazine hydrate; nickel; In ethanol; acetone;

Reference yield:

: 67291-72-9
2-chloro-N-(2-methoxy-4-nitrophenyl)acetamide

: 110506-40-6
N-(4-Amino-2-methoxy-phenyl)-2-(4-phenyl-piperazin-1-yl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / K₂CO₃ / acetone / 4 h / Heating

2: 73 percent / 100percent N₂H₄*H₂O / Raney nickel / ethanol / 2 h / Heating

With potassium carbonate; hydrazine hydrate; nickel; In ethanol; acetone;