methyl 3,4-di-O-benzyl-2-O-levulinoyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside

Base Information

Chemical Name:methyl 3,4-di-O-benzyl-2-O-levulinoyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside
CAS No.:866885-24-7
Molecular Formula:C₄₂H₅₀O₁₀Si
Molecular Weight:742.939
Hs Code.:

Synonyms:methyl 3,4-di-O-benzyl-2-O-levulinoyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside

Suppliers and Price of methyl 3,4-di-O-benzyl-2-O-levulinoyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 3,4-di-O-benzyl-2-O-levulinoyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 3,4-di-O-benzyl-2-O-levulinoyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside

There total 19 articles about methyl 3,4-di-O-benzyl-2-O-levulinoyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 866885-23-6
methyl 3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside

: 123-76-2
levulinic acid

: 866885-24-7
methyl 3,4-di-O-benzyl-2-O-levulinoyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside

Guidance literature:: levulinic acid; With dmap; (2-chloropropyl)dimethylamine hydrochloride; In dichloromethane; at 0 ℃; for 0.166667h;

methyl 3,4-di-O-benzyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside; In dichloromethane; at 20 ℃; for 15h;
DOI:10.1081/CAR-200067008

Reference yield:

: 866885-19-0
dimethyl(2-naphthylmethyl)vinylsilane

: 866885-24-7
methyl 3,4-di-O-benzyl-2-O-levulinoyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1.1: 9-borabicyclo[3.3.1]nonane / tetrahydrofuran / 1 h / 20 °C

1.2: 58 percent / hydrogen peroxide; sodium hydroxide / ethanol; H₂O / 1 h / Heating

2.1: 63 percent / diethyl ether; toluene / 2.5 h / -15 - 20 °C

3.1: 98 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 15 h / 20 °C

4.1: dimethyldioxirane / CH₂Cl₂; acetone / 1 h / 0 °C

5.1: 0.683 g / CH₂Cl₂ / 15 h / 20 °C

6.1: 4-(dimethylamino)pyridine; 2-dimethylaminoisopropyl chloride hydrochloride / CH₂Cl₂ / 0.17 h / 0 °C

6.2: 90 percent / CH₂Cl₂ / 15 h / 20 °C

With dmap; 3,3-dimethyldioxirane; (2-chloropropyl)dimethylamine hydrochloride; 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; diethyl ether; dichloromethane; acetone; toluene;
DOI:10.1081/CAR-200067008

Reference yield:

: 866885-20-3
2-[dimethyl(2-naphthylmethyl)silyl]ethanol

: 866885-24-7
methyl 3,4-di-O-benzyl-2-O-levulinoyl-6-O-{2-[dimethyl(2-naphthylmethyl)silyl]ethoxycarbonyl}-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1.1: 63 percent / diethyl ether; toluene / 2.5 h / -15 - 20 °C

2.1: 98 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 15 h / 20 °C

3.1: dimethyldioxirane / CH₂Cl₂; acetone / 1 h / 0 °C

4.1: 0.683 g / CH₂Cl₂ / 15 h / 20 °C

5.1: 4-(dimethylamino)pyridine; 2-dimethylaminoisopropyl chloride hydrochloride / CH₂Cl₂ / 0.17 h / 0 °C

5.2: 90 percent / CH₂Cl₂ / 15 h / 20 °C

With dmap; 3,3-dimethyldioxirane; (2-chloropropyl)dimethylamine hydrochloride; In diethyl ether; dichloromethane; acetone; toluene;
DOI:10.1081/CAR-200067008