N-(2-(2,2-difluoro-2-(phenylthio)ethylamino)-2-oxo-1-phenylethyl)-N-(4-methoxyphenyl)pentanamide

Base Information

Chemical Name:N-(2-(2,2-difluoro-2-(phenylthio)ethylamino)-2-oxo-1-phenylethyl)-N-(4-methoxyphenyl)pentanamide
CAS No.:1233199-93-3
Molecular Formula:C₂₈H₃₀F₂N₂O₃S
Molecular Weight:512.621
Hs Code.:

Synonyms:N-(2-(2,2-difluoro-2-(phenylthio)ethylamino)-2-oxo-1-phenylethyl)-N-(4-methoxyphenyl)pentanamide

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Chemical Property of N-(2-(2,2-difluoro-2-(phenylthio)ethylamino)-2-oxo-1-phenylethyl)-N-(4-methoxyphenyl)pentanamide

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Technology Process of N-(2-(2,2-difluoro-2-(phenylthio)ethylamino)-2-oxo-1-phenylethyl)-N-(4-methoxyphenyl)pentanamide

There total 1 articles about N-(2-(2,2-difluoro-2-(phenylthio)ethylamino)-2-oxo-1-phenylethyl)-N-(4-methoxyphenyl)pentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1233199-78-4
(1,1-difluoro-2-isocyanoethyl)(phenyl)sulfane

: 100-52-7
benzaldehyde

: 104-94-9
4-methoxy-aniline

: 109-52-4
valeric acid

: 1233199-93-3
N-(2-(2,2-difluoro-2-(phenylthio)ethylamino)-2-oxo-1-phenylethyl)-N-(4-methoxyphenyl)pentanamide

Guidance literature:: benzaldehyde; 4-methoxy-aniline; at 20 ℃; for 0.583333h; Neat (no solvent);

(1,1-difluoro-2-isocyanoethyl)(phenyl)sulfane; valeric acid; at 60 ℃; for 1h; Neat (no solvent);
DOI:10.1039/c000835d

Reference yield: 52.0%

: 1233199-93-3
N-(2-(2,2-difluoro-2-(phenylthio)ethylamino)-2-oxo-1-phenylethyl)-N-(4-methoxyphenyl)pentanamide

: 1233200-04-8
N-(2-(2,2-difluoroethylamino)-2-oxo-1-phenylethyl)-N-(4-methoxyphenyl)pentanamide

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 90 ℃; for 16h; Inert atmosphere;
DOI:10.1039/c000835d