trans-2-oxo-oxazolidine-4-carboxylic acid (1-benzenesulfonyl-4-[4-(2,2,2-trifluoro-ethylamino)-cyclohexylamino]-1H-pyrrolo[2,3-b]pyridin-5-yl)-amide

Base Information

Chemical Name:trans-2-oxo-oxazolidine-4-carboxylic acid (1-benzenesulfonyl-4-[4-(2,2,2-trifluoro-ethylamino)-cyclohexylamino]-1H-pyrrolo[2,3-b]pyridin-5-yl)-amide
CAS No.:1418200-32-4
Molecular Formula:C₂₅H₂₇F₃N₆O₅S
Molecular Weight:580.588
Hs Code.:

trans-2-oxo-oxazolidine-4-carboxylic acid (1-benzenesulfonyl-4-[4-(2,2,2-trifluoro-ethylamino)-cyclohexylamino]-1H-pyrrolo[2,3-b]pyridin-5-yl)-amide

Synonyms:trans-2-oxo-oxazolidine-4-carboxylic acid (1-benzenesulfonyl-4-[4-(2,2,2-trifluoro-ethylamino)-cyclohexylamino]-1H-pyrrolo[2,3-b]pyridin-5-yl)-amide

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Chemical Property of trans-2-oxo-oxazolidine-4-carboxylic acid (1-benzenesulfonyl-4-[4-(2,2,2-trifluoro-ethylamino)-cyclohexylamino]-1H-pyrrolo[2,3-b]pyridin-5-yl)-amide

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Technology Process of trans-2-oxo-oxazolidine-4-carboxylic acid (1-benzenesulfonyl-4-[4-(2,2,2-trifluoro-ethylamino)-cyclohexylamino]-1H-pyrrolo[2,3-b]pyridin-5-yl)-amide

There total 1 articles about trans-2-oxo-oxazolidine-4-carboxylic acid (1-benzenesulfonyl-4-[4-(2,2,2-trifluoro-ethylamino)-cyclohexylamino]-1H-pyrrolo[2,3-b]pyridin-5-yl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89033-27-2
2-oxo-4(S)-oxazolidine carboxylic acid

: 1418200-53-9
trans-1-benzenesulfonyl-N₄-[4-(2,2,2-trifluoro-ethylamino)-cyclohexyl]-1H-pyrrolo[2,3-b]pyridine-4,5-diamine

: 1418200-32-4
trans-2-oxo-oxazolidine-4-carboxylic acid (1-benzenesulfonyl-4-[4-(2,2,2-trifluoro-ethylamino)-cyclohexylamino]-1H-pyrrolo[2,3-b]pyridin-5-yl)-amide

Guidance literature:: With pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; at 60 ℃; for 1.5h;

Reference yield:

: 1418200-32-4
trans-2-oxo-oxazolidine-4-carboxylic acid (1-benzenesulfonyl-4-[4-(2,2,2-trifluoro-ethylamino)-cyclohexylamino]-1H-pyrrolo[2,3-b]pyridin-5-yl)-amide

: 1418200-33-5
trans-4-(6-benzenesulfonyl-1-[4-(2,2,2-trifluoro-ethylamino)-cyclohexyl]-1,6-dihydro-1,3,5,6-tetraaza-as-indacen-2-yl)-oxazolidin-2-one

Guidance literature:: With acetic acid; at 80 ℃; for 18h;

Reference yield:

: 1418200-32-4
trans-2-oxo-oxazolidine-4-carboxylic acid (1-benzenesulfonyl-4-[4-(2,2,2-trifluoro-ethylamino)-cyclohexylamino]-1H-pyrrolo[2,3-b]pyridin-5-yl)-amide

: 1418198-91-0
trans-4-(1-[4-(2,2,2-trifluoro-ethylamino)-cyclohexyl]-1,6-dihydro-1,3,5,6-tetraaza-as-indacen-2-yl)-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 18 h / 80 °C

2: sodium hydroxide / water; isopropyl alcohol / 18 h / 50 °C

With acetic acid; sodium hydroxide; In water; isopropyl alcohol;