4-Acetyl-5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

Base Information

Chemical Name:4-Acetyl-5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole
CAS No.:188539-68-6
Molecular Formula:C₁₃H₇Cl₂F₃N₄O
Molecular Weight:363.126
Hs Code.:

Synonyms:4-Acetyl-5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

Suppliers and Price of 4-Acetyl-5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Acetyl-5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

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Technology Process of 4-Acetyl-5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

There total 5 articles about 4-Acetyl-5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 188538-68-3
5-Amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-ethynylpyrazole

: 188539-68-6
4-Acetyl-5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

Guidance literature:: With toluene-4-sulfonic acid; In acetonitrile;

Reference yield:

: 120068-79-3
5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

: 188539-68-6
4-Acetyl-5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

Guidance literature:: Multi-step reaction with 4 steps

1: N-iodo-succinimide

2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide

3: potassium carbonate

4: toluene-4-sulfonic acid

With bis-triphenylphosphine-palladium(II) chloride; N-iodo-succinimide; copper(l) iodide; potassium carbonate; toluene-4-sulfonic acid; 2: |Sonogashira Cross-Coupling;
DOI:10.1016/j.envint.2017.03.012

Reference yield:

: 188538-67-2
5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trimethylsilylethynylpyrazole

: 188539-68-6
4-Acetyl-5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate

2: toluene-4-sulfonic acid

With potassium carbonate; toluene-4-sulfonic acid;
DOI:10.1016/j.envint.2017.03.012