1,3-Dichloro-2,2-difluoropropane

Base Information

• Chemical Name: 1,3-Dichloro-2,2-difluoropropane
• CAS No.: 1112-36-3
• Molecular Formula: C₃H₄Cl₂F₂
• Molecular Weight: 148.968
• Hs Code.: 2903791090
• DSSTox Substance ID: DTXSID40445951
• Nikkaji Number: J570.720J
• Wikidata: Q82264504
• Mol file: 1112-36-3.mol

Synonyms:1,3-DICHLORO-2,2-DIFLUOROPROPANE;1112-36-3;Propane,1,3-dichloro-2,2-difluoro-;HCFC-252caca;SCHEMBL1991316;DTXSID40445951;UOHYSKIMXVGQBL-UHFFFAOYSA-N;AKOS006382780

Chemical Property of 1,3-Dichloro-2,2-difluoropropane

Chemical Property:

• Refractive Index: 1.3633 (estimate)
• Boiling Point: 44.18°C (rough estimate)
• PSA: 0.00000
• Density: 1.5635 (estimate)
• LogP: 2.09930
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 147.9658118
• Heavy Atom Count: 7
• Complexity: 48.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(CCl)(F)F)Cl

Technology Process of 1,3-Dichloro-2,2-difluoropropane

There total 12 articles about 1,3-Dichloro-2,2-difluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

2,3-Dichloroprop-1-ene (78-88-6) → 1,3-dichloro-2,2-difluoropropane (1112-36-3) + 1-Bromo-2,3-dichloro-2-fluoro-propane (111483-25-1)

Guidance literature:

With bromine trifluoride; In 1,1,2-Trichloro-1,2,2-trifluoroethane; at 10 - 20 ℃;

Reference yield:

1,2,2,3-tetrachloropropane (13116-53-5) → 1,3-dichloro-2,2-difluoropropane (1112-36-3)

Guidance literature:

With hydrogen fluoride; mercury(II) oxide; at 125 ℃;

DOI:10.1021/ja01252a029

Reference yield:

3-chloro-2,2-difluoro-1-propanol (33420-47-2) → 1,3-dichloro-2,2-difluoropropane (1112-36-3)

Guidance literature:

With phosphorus pentachloride; at 150 - 170 ℃;

upstream raw materials:

1,2,2,3-tetrachloropropane

3-chloro-2-fluoropropene

3-chloro-2,2-difluoro-1-propanol

2,3-Dichloroprop-1-ene

Downstream raw materials:

1,1,1,3-tetrachloro-2,2-difluoropropane

1,1,1,3,3,3-hexachloro-2,2-difluoro-propane

1,3-difluoro-2,2-difluoropropane

1,2,2-trifluoro-3-chloropropane