4,4'-(4,4'-(cyclopent-1-ene-1,2-diyl)bis(5-methylthiophene-4,2-diyl))-dibenzoic acid

Base Information

• Chemical Name: 4,4'-(4,4'-(cyclopent-1-ene-1,2-diyl)bis(5-methylthiophene-4,2-diyl))-dibenzoic acid
• CAS No.: 732304-39-1
• Molecular Formula: C₂₉H₂₄O₄S₂
• Molecular Weight: 500.639
• Mol file: 732304-39-1.mol

Synonyms:4,4'-(4,4'-(cyclopent-1-ene-1,2-diyl)bis(5-methylthiophene-4,2-diyl))-dibenzoic acid

Chemical Property of 4,4'-(4,4'-(cyclopent-1-ene-1,2-diyl)bis(5-methylthiophene-4,2-diyl))-dibenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4'-(4,4'-(cyclopent-1-ene-1,2-diyl)bis(5-methylthiophene-4,2-diyl))-dibenzoic acid

There total 8 articles about 4,4'-(4,4'-(cyclopent-1-ene-1,2-diyl)bis(5-methylthiophene-4,2-diyl))-dibenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,2-bis(5-(4-ethyloxycarbonylphenyl)-2-methylthien-3-yl)cyclopent-1-ene → 4,4'-(4,4'-(cyclopent-1-ene-1,2-diyl)bis(5-methylthiophene-4,2-diyl))-dibenzoic acid (732304-39-1)

Guidance literature:

With potassium hydroxide; In 1,4-dioxane; Reflux;

DOI:10.1002/anie.201602417

Reference yield: 93.3%

1,2-bis[5'-(4''-methoxycarbonylphenyl)-2'-methylthien-3'-yl]cyclopentene → 4,4'-(4,4'-(cyclopent-1-ene-1,2-diyl)bis(5-methylthiophene-4,2-diyl))-dibenzoic acid (732304-39-1)

Guidance literature:

With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 20 ℃; for 6h;

DOI:10.1016/j.cclet.2016.01.056

Reference yield: 81.0%

carbon dioxide (124-38-9,18923-20-1) + 1,2-bis(5'-(4-bromophenyl)-2'-methylthien-3'-yl)-cyclopentene (532930-53-3) → 4,4'-(4,4'-(cyclopent-1-ene-1,2-diyl)bis(5-methylthiophene-4,2-diyl))-dibenzoic acid (732304-39-1)

Guidance literature:

1,2-bis(5'-(4"-bromophenyl)-2'-methylthien-3'-yl)-cyclopentene; With n-butyllithium; In tetrahydrofuran; hexane; at -55 ℃; for 1h;

carbon dioxide; In tetrahydrofuran; hexane; at -55 ℃; for 1.5h;

DOI:10.1039/b802580k

upstream raw materials:

carbon dioxide

1,2-bis(5'-(4-bromophenyl)-2'-methylthien-3'-yl)-cyclopentene

1,2-bis(5-chloro-2-methylthien-3-yl)cyclopent-1-ene

1,2-bis(5-boronic acid-2-methyl-3-thienyl)cyclopentene

Downstream raw materials:

1,2-bis[2-methyl-5-(p-N-dodecylureidophenyl)-3-thienyl]cyclopentene

1,2-bis[2-methyl-5-(p-N-hexylureidophenyl)-3-thienyl]cyclopentene