C₂₄H₃₄O₅Si

Base Information

• Chemical Name: C₂₄H₃₄O₅Si
• CAS No.: 106569-74-8
• Molecular Formula: C₂₄H₃₄O₅Si
• Molecular Weight: 430.616
• Mol file: 106569-74-8.mol

Synonyms:C₂₄H₃₄O₅Si

Chemical Property of C₂₄H₃₄O₅Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₃₄O₅Si

There total 37 articles about C₂₄H₃₄O₅Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-octynolic acid (76469-08-4) → C24H34O5Si (106569-74-8)

Guidance literature:

Multi-step reaction with 17 steps

1: (COCl)2

2: 1) nBuLi / 1) THF

3: 1) (Me₂Si)2NLi / 1) THF, -78 deg C, 2) THF, -78 to 0 deg C

4: LiAlH₄ / tetrahydrofuran

5: KH / tetrahydrofuran

6: 1) ozone

7: 98 percent / hydrogen, quinoline / 5percent Pd/CaCO₃ / hexane

8: Me₂AlCl / CH₂Cl₂

10: ozone

11: 1) t-BuLi / 1) THF, 2) THF, HMPA

12: H₃O⁽¹⁺⁾

13: 1) DMSO, (COCl)2, 2) Et₃N / 1) -78 deg C, 2) -78 to -10 deg C

14: ZnBr₂ / CH₂Cl₂

15: CSA / benzene

16: 79 percent / tetrahydrofuran; dimethylsulfoxide

17: 1) LDA

With quinoline; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; (Me₂Si)2NLi; camphor-10-sulfonic acid; oxonium; hydrogen; tert.-butyl lithium; dimethylaluminum chloride; potassium hydride; ozone; dimethyl sulfoxide; triethylamine; zinc dibromide; lithium diisopropyl amide; Lindlar's catalyst; In tetrahydrofuran; hexane; dichloromethane; dimethyl sulfoxide; benzene;

DOI:10.1021/ja00238a060

Reference yield:

benzyl bromide (100-39-0) → C24H34O5Si (106569-74-8)

Guidance literature:

Multi-step reaction with 13 steps

1: KH / tetrahydrofuran

2: 1) ozone

3: 98 percent / hydrogen, quinoline / 5percent Pd/CaCO₃ / hexane

4: Me₂AlCl / CH₂Cl₂

6: ozone

7: 1) t-BuLi / 1) THF, 2) THF, HMPA

8: H₃O⁽¹⁺⁾

9: 1) DMSO, (COCl)2, 2) Et₃N / 1) -78 deg C, 2) -78 to -10 deg C

10: ZnBr₂ / CH₂Cl₂

11: CSA / benzene

12: 79 percent / tetrahydrofuran; dimethylsulfoxide

13: 1) LDA

With quinoline; oxalyl dichloride; camphor-10-sulfonic acid; oxonium; hydrogen; tert.-butyl lithium; dimethylaluminum chloride; potassium hydride; ozone; dimethyl sulfoxide; triethylamine; zinc dibromide; lithium diisopropyl amide; Lindlar's catalyst; In tetrahydrofuran; hexane; dichloromethane; dimethyl sulfoxide; benzene;

DOI:10.1021/ja00238a060

Reference yield:

5-octynoyl chloride (106569-63-5) → C24H34O5Si (106569-74-8)

Guidance literature:

Multi-step reaction with 16 steps

1: 1) nBuLi / 1) THF

2: 1) (Me₂Si)2NLi / 1) THF, -78 deg C, 2) THF, -78 to 0 deg C

3: LiAlH₄ / tetrahydrofuran

4: KH / tetrahydrofuran

5: 1) ozone

6: 98 percent / hydrogen, quinoline / 5percent Pd/CaCO₃ / hexane

7: Me₂AlCl / CH₂Cl₂

9: ozone

10: 1) t-BuLi / 1) THF, 2) THF, HMPA

11: H₃O⁽¹⁺⁾

12: 1) DMSO, (COCl)2, 2) Et₃N / 1) -78 deg C, 2) -78 to -10 deg C

13: ZnBr₂ / CH₂Cl₂

14: CSA / benzene

15: 79 percent / tetrahydrofuran; dimethylsulfoxide

16: 1) LDA

With quinoline; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; (Me₂Si)2NLi; camphor-10-sulfonic acid; oxonium; hydrogen; tert.-butyl lithium; dimethylaluminum chloride; potassium hydride; ozone; dimethyl sulfoxide; triethylamine; zinc dibromide; lithium diisopropyl amide; Lindlar's catalyst; In tetrahydrofuran; hexane; dichloromethane; dimethyl sulfoxide; benzene;

DOI:10.1021/ja00238a060

upstream raw materials:

chloro-trimethyl-silane

C₂₁H₂₆O₅

Tetrahydro-4H-pyran-4-one

5-octynolic acid