ethyl 6-hydroxy-2,4-dioxo-3-(phenylmethyl)-1-(2-pyridinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Base Information

Chemical Name:ethyl 6-hydroxy-2,4-dioxo-3-(phenylmethyl)-1-(2-pyridinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS No.:960540-90-3
Molecular Formula:C₁₉H₁₇N₃O₅
Molecular Weight:367.361
Hs Code.:

Synonyms:ethyl 6-hydroxy-2,4-dioxo-3-(phenylmethyl)-1-(2-pyridinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Suppliers and Price of ethyl 6-hydroxy-2,4-dioxo-3-(phenylmethyl)-1-(2-pyridinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 6-hydroxy-2,4-dioxo-3-(phenylmethyl)-1-(2-pyridinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of ethyl 6-hydroxy-2,4-dioxo-3-(phenylmethyl)-1-(2-pyridinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

There total 3 articles about ethyl 6-hydroxy-2,4-dioxo-3-(phenylmethyl)-1-(2-pyridinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

: 5080-26-2
diethyl {[(phenylmethyl)amino]carbonyl}propanedioate

: 4737-19-3
2-isocyanatopyridine

: 960540-90-3
ethyl 6-hydroxy-2,4-dioxo-3-(phenylmethyl)-1-(2-pyridinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Guidance literature:: With sodium hydride; In 1,4-dioxane; at 110 ℃; for 1h; Microwave;

Reference yield:

: 98-98-6
2-Picolinic acid

: 960540-90-3
ethyl 6-hydroxy-2,4-dioxo-3-(phenylmethyl)-1-(2-pyridinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: diphenyl phosphoryl azide; triethylamine / toluene / 2.5 h / 20 - 80 °C

2: sodium hydride / 1,4-dioxane / 1 h / 110 °C / Microwave

With diphenyl phosphoryl azide; sodium hydride; triethylamine; In 1,4-dioxane; toluene;

Reference yield:

: 3173-56-6
benzyl isothiocyanate

: 960540-90-3
ethyl 6-hydroxy-2,4-dioxo-3-(phenylmethyl)-1-(2-pyridinyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / 0.25 h / 20 °C

1.2: 3 h / 60 °C

2.1: sodium hydride / 1,4-dioxane / 1 h / 110 °C / Microwave

With sodium hydride; In tetrahydrofuran; 1,4-dioxane;