Technology Process of 7-<2-(benzoyloxy)-3-amino>propoxy>flavone
There total 10 articles about 7-<2-(benzoyloxy)-3-amino>propoxy>flavone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
triethylamine;
In
dichloromethane;
Ambient temperature;
DOI:10.1021/jm00121a034
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 63 percent / K2CO3 / acetone / Heating
2: 85 percent / NaOAc, glacial acetic acid / 16 h / Heating
3: 72 percent / NaOH / H2O; propan-2-ol / 2 h / 70 °C
5: 86 percent / H2, HOAc / 10percentPd/C / methanol
6: 52 percent / NEt3 / CH2Cl2 / 4 h / Heating
7: 56 percent / NEt3 / CH2Cl2 / Ambient temperature
With
sodium hydroxide; hydrogen; sodium acetate; potassium carbonate; acetic acid; triethylamine;
10% palladium on active carbon;
In
methanol; dichloromethane; water; isopropyl alcohol; acetone;
DOI:10.1021/jm00121a034
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1) Na-benzoate, 2) KOH / 1) 180-190 deg C, 6 h, 2) C2H5OH, H2O, reflux, 30 min
2: 72 percent / NaOH / H2O; propan-2-ol / 2 h / 70 °C
4: 86 percent / H2, HOAc / 10percentPd/C / methanol
5: 52 percent / NEt3 / CH2Cl2 / 4 h / Heating
6: 56 percent / NEt3 / CH2Cl2 / Ambient temperature
With
sodium benzoate; potassium hydroxide; sodium hydroxide; hydrogen; acetic acid; triethylamine;
10% palladium on active carbon;
In
methanol; dichloromethane; water; isopropyl alcohol;
DOI:10.1021/jm00121a034