2-(4-Aminophenyl)quinoline-4-carboxylic acid

Base Information

• Chemical Name: 2-(4-Aminophenyl)quinoline-4-carboxylic acid
• CAS No.: 94205-62-6
• Molecular Formula: C16H12 N2 O2
• Molecular Weight: 264.283
• Hs Code.: 2933499090
• European Community (EC) Number: 673-273-2
• Mol file: 94205-62-6.mol

Synonyms:2-(4-aminophenyl)quinoline-4-carboxylic acid;94205-62-6;2-(4-Amino-phenyl)-quinoline-4-carboxylic acid;2-(4-aminophenyl)quinoline-4-carboxylicacid;CBMicro_023465;2-(4-aminophenyl)-quinoline-4-carboxylic acid;Oprea1_351345;Oprea1_746802;IFLab1_001711;SCHEMBL16921273;HMS1416N17;BBL013562;MFCD00178260;STK364468;AKOS000300087;CCG-103972;SB68710;VS-03863;CS-0313349;FT-0642266;4-Quinolinecarboxylicacid,2-(4-aminophenyl)-;A844870

Chemical Property of 2-(4-Aminophenyl)quinoline-4-carboxylic acid

Chemical Property:

• Vapor Pressure: 7.19E-11mmHg at 25°C
• Melting Point: 174-176 °C(Solv: N,N-dimethylformamide (68-12-2); water (7732-18-5))
• Boiling Point: 501.3°Cat760mmHg
• PKA: 0.79±0.10(Predicted)
• Flash Point: 257°C
• PSA: 76.21000
• Density: g/cm³
• LogP: 3.76340
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 264.089877630
• Heavy Atom Count: 20
• Complexity: 352

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Amino-phenyl)-quinoline-4-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(=CC(=N2)C3=CC=C(C=C3)N)C(=O)O

Technology Process of 2-(4-Aminophenyl)quinoline-4-carboxylic acid

There total 2 articles about 2-(4-Aminophenyl)quinoline-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

indole-2,3-dione (91-56-5,1186480-61-4,84788-92-1) + p-aminobenzophenone (99-92-3) → 2-(4'-aminophenyl)-4-quinolinecarboxylic acid (94205-62-6)

Guidance literature:

With water; potassium hydroxide; In ethanol; at 100 ℃;

Reference yield:

→ 2-(4'-aminophenyl)-4-quinolinecarboxylic acid (94205-62-6)

Guidance literature:

With sodium sulfide; water;

Reference yield: 96.2%

2-(4'-aminophenyl)-4-quinolinecarboxylic acid (94205-62-6) + 4-(4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzenesulfonic acid (89-36-1) → 2-(4-{N'-[3-methyl-5-oxo-1-(4-sulfo-phenyl)-1,5-dihydro-pyrazol-4-ylidene]-hydrazino}-phenyl)-quinoline-4-carboxylic acid

Guidance literature:

2-(4'-aminophenyl)-4-quinolinecarboxylic acid; With hydrogenchloride; sodium nitrite; at 0 ℃;

4-(4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzenesulfonic acid; With sodium hydroxide; at 60 ℃;

With sodium hydroxide; sodium carbonate; at 5 - 8 ℃; pH=8.5;

DOI:10.1023/A:1014783307934

upstream raw materials:

indole-2,3-dione

p-aminobenzophenone

Downstream raw materials:

2-(4-acetamidophenyl)quinoline-4-carboxylic acid

2-[4-aminophenyl]quinoline

2-[4-(2-hydroxyimino-acetylamino)-phenyl]-quinoline-4-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 94205-62-6 2-(4-AMINO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID

Send

Send

Metric Ton KG G Pound L ML

Send

Send