2-[4-(Acetylamino)phenyl]quinoline-4-carboxylic acid

Base Information

Chemical Name:2-[4-(Acetylamino)phenyl]quinoline-4-carboxylic acid
CAS No.:298187-85-6
Molecular Formula:C₁₈H₁₄N₂O₃
Molecular Weight:306.321
Hs Code.:
DSSTox Substance ID:DTXSID20351460
Wikidata:Q82127890
ChEMBL ID:CHEMBL1403108
Mol file:298187-85-6.mol

Synonyms:298187-85-6;2-[4-(acetylamino)phenyl]quinoline-4-carboxylic acid;2-(4-acetamidophenyl)quinoline-4-carboxylic acid;CHEMBL1403108;4-Quinolinecarboxylicacid, 2-[4-(acetylamino)phenyl]-;Maybridge1_006239;Oprea1_288838;MLS000778038;SCHEMBL5154506;2-(4-(Acetyl amino)phenyl)quinoline-4-carboxylic acid;HMS559D13;DTXSID20351460;HMS2749A06;BDBM50430813;STK057713;AKOS001671262;SMR000414432;EU-0080447;FT-0706664;SR-01000505511;SR-01000505511-1;2-(4-Acetylamino-phenyl)-quinoline-4-carboxylic acid;2-[4-(ACETYLAMINO)PHENYL]QUINOLINE-4-CARBOXYLICACID

Suppliers and Price of 2-[4-(Acetylamino)phenyl]quinoline-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-[4-(ACETYLAMINO)PHENYL]QUINOLINE-4-CARBOXYLIC ACID 95.00%
1G
$ 669.44

Total 7 raw suppliers

Chemical Property of 2-[4-(Acetylamino)phenyl]quinoline-4-carboxylic acid

Chemical Property:

Vapor Pressure:5.19E-15mmHg at 25°C
Melting Point:274.5 °C
Refractive Index:1.699
Boiling Point:595.2°Cat760mmHg
Flash Point:313.7°C
PSA：79.29000
Density:1.345g/cm³
LogP:3.63140
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:306.10044231
Heavy Atom Count:23
Complexity:446

Purity/Quality:

98%min ^*data from raw suppliers

2-[4-(ACETYLAMINO)PHENYL]QUINOLINE-4-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=C2)C(=O)O

Technology Process of 2-[4-(Acetylamino)phenyl]quinoline-4-carboxylic acid

There total 5 articles about 2-[4-(Acetylamino)phenyl]quinoline-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 94205-62-6
2-(4'-aminophenyl)-4-quinolinecarboxylic acid

: 108-24-7
acetic anhydride

: 298187-85-6
2-(4-acetamidophenyl)quinoline-4-carboxylic acid

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 2h;

Reference yield:

: 94205-62-6
2-(4'-aminophenyl)-4-quinolinecarboxylic acid

: 75-36-5
acetyl chloride

: 298187-85-6
2-(4-acetamidophenyl)quinoline-4-carboxylic acid

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 0 ℃;

Reference yield:

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 298187-85-6
2-(4-acetamidophenyl)quinoline-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: water; potassium hydroxide / ethanol / 100 °C

2: triethylamine / dichloromethane / 2 h / 0 - 20 °C

With water; triethylamine; potassium hydroxide; In ethanol; dichloromethane;