1,2,4,5-Cyclohexanetetracarboxylic Dianhydride

Base Information

• Chemical Name: 1,2,4,5-Cyclohexanetetracarboxylic Dianhydride
• CAS No.: 2754-41-8
• Molecular Formula: C10H8O6
• Molecular Weight: 224.17
• Hs Code.: 29321900
• European Community (EC) Number: 691-475-9
• DSSTox Substance ID: DTXSID00560497
• Nikkaji Number: J1.581.893J
• Mol file: 2754-41-8.mol

Synonyms:2754-41-8;1,2,4,5-Cyclohexanetetracarboxylic Dianhydride;Tetrahydrobenzo[1,2-c:4,5-c']difuran-1,3,5,7(3aH,7aH)-tetraone;1H,3H-Benzo[1,2-c:4,5-c']difuran-1,3,5,7-tetrone, hexahydro-;3a,4,4a,7a,8,8a-hexahydrofuro[3,4-f][2]benzofuran-1,3,5,7-tetrone;1,2,4,5-Cyclohexanetetracarboxylic acid dianhydride;H-PMDA;MFCD13704912;1,2,4,5-cyclohexanetetracarboxylic dianhydride (HPMDA);Hexahydro-1H,3H-benzo[1,2-c:4,5-c']difuran-1,3,5,7-tetrone;3a,4,4a,7a,8,8a-hexahydrofuro[3,4-f]isobenzofuran-1,3,5,7-tetrone;1,2,4,5-Cyclohexanetetracarboxylic Dianhydride (purified by sublimation);1,2,4,5-CyclohexanetetracarboxylicDianhydride;SCHEMBL615001;DTXSID00560497;AMY11245;AKOS015915352;AS-31782;SY007734;C2419;C2919;CS-0155455;A819113;A843128;tetrahydroisobenzofuro[5,6-c]furan-1,3,5,7(3aH,7aH)-tetraone

Chemical Property of 1,2,4,5-Cyclohexanetetracarboxylic Dianhydride

Chemical Property:

• Melting Point: 240°C(lit.)
• Boiling Point: 517.531 °C at 760 mmHg
• Flash Point: 238.633 °C
• PSA: 86.74000
• Density: 1.568 g/cm³
• LogP: -0.58820
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility.: soluble in Acetone
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 224.03208797
• Heavy Atom Count: 16
• Complexity: 349

Purity/Quality:

99%, ^*data from raw suppliers

1,2,4,5-Cyclohexanetetracarboxylic Dianhydride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C2C(CC3C1C(=O)OC3=O)C(=O)OC2=O
• Uses: 1,2,4,5-Cyclohexanetetracarboxylic dianhydride can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development and chemical and pharmaceutical production processes.

Technology Process of 1,2,4,5-Cyclohexanetetracarboxylic Dianhydride

There total 10 articles about 1,2,4,5-Cyclohexanetetracarboxylic Dianhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.5%

cyclohexane-1e,2a,4a,5e-tetracarboxylic acid (15383-49-0) → 1,2,4,5-cyclohexanetetracarboxylic acid-1,2:4,5-dianhydride (2754-41-8)

Guidance literature:

With acetic anhydride; for 1h; Inert atmosphere; Reflux;

Reference yield: 82.8%

tetraethyl 1,2,4,5-cyclohexanetetracarboxylate (94253-98-2) → 1,2,4,5-cyclohexanetetracarboxylic acid-1,2:4,5-dianhydride (2754-41-8)

Guidance literature:

With sulfuric acid; acetic acid; In 5,5-dimethyl-1,3-cyclohexadiene; at 130 ℃; for 5h; Temperature;

Reference yield: 76.0%

cyclohexane-1,2,4,5-tetracarboxylic acid tetramethyl ester (92298-55-0) → 1,2,4,5-cyclohexanetetracarboxylic acid-1,2:4,5-dianhydride (2754-41-8)

Guidance literature:

With sulfuric acid; acetic acid; at 128 ℃; for 10h; Time;

upstream raw materials:

cyclohexane-1e,2a,4a,5e-tetracarboxylic acid

1,2,4,5-benzenetetracarboxylic acid

Pyromellitic dianhydride

tetramethyl 1,2,4,5-benzenetetracarboxylate

Downstream raw materials:

1,2,4,5-Tetrakis-hydroxymethyl-cyclohexan