Tetramethyl pyromellitate

Base Information

• Chemical Name: Tetramethyl pyromellitate
• CAS No.: 635-10-9
• Molecular Formula: C14H14 O8
• Molecular Weight: 310.26
• Hs Code.: 29333999
• European Community (EC) Number: 211-226-6
• NSC Number: 4188
• UNII: AG5F4XJK7L
• DSSTox Substance ID: DTXSID50212898
• Nikkaji Number: J3.313H
• Mol file: 635-10-9.mol

Synonyms:Tetramethyl pyromellitate;635-10-9;Tetramethyl benzene-1,2,4,5-tetracarboxylate;Pyromellitic acid tetramethyl ester;Tetramethyl 1,2,4,5-benzenetetracarboxylate;1,2,4,5-Benzenetetracarboxylic acid, tetramethyl ester;AG5F4XJK7L;C14H14O8;NSC-4188;EINECS 211-226-6;AI3-06467;UNII-AG5F4XJK7L;TimTec1_000822;SCHEMBL829753;1,2,4,5-tetramethyl benzene-1,2,4,5-tetracarboxylate;DTXSID50212898;NSC4188;HMS1536F08;NSC 4188;MFCD00014903;AKOS004903721;AS-58624;Tetramethyl 1,4,5-benzenetetracarboxylate;CS-0145251;FT-0676076;E79087;1,4,5-Benzenetetracarboxylic acid, tetramethyl ester

Chemical Property of Tetramethyl pyromellitate

Chemical Property:

• Vapor Pressure: 1.07E-05mmHg at 25°C
• Melting Point: 143-144°C
• Refractive Index: 1.5500 (estimate)
• Boiling Point: 370.9°C at 760 mmHg
• Flash Point: 161.5°C
• PSA: 105.20000
• Density: 1.287g/cm³
• LogP: 0.83300
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 8
• Exact Mass: 310.06886740
• Heavy Atom Count: 22
• Complexity: 376

Purity/Quality:

99% ^*data from raw suppliers

TETRAMETHYL 1,2,4,5-BENZENETETRACARBOXYLATE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC(=O)C1=CC(=C(C=C1C(=O)OC)C(=O)OC)C(=O)OC

Technology Process of Tetramethyl pyromellitate

There total 34 articles about Tetramethyl pyromellitate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.9%

Pyromellitic dianhydride (89-32-7,34527-94-1) + trimethyl orthoformate (149-73-5) → tetramethyl 1,2,4,5-benzenetetracarboxylate (635-10-9)

Guidance literature:

In methanol; for 7.5h; Heating;

DOI:10.1021/jo800543w

Reference yield: 95.0%

methanol (67-56-1) + C12H10O8 → tetramethyl 1,2,4,5-benzenetetracarboxylate (635-10-9)

Guidance literature:

With thionyl chloride; at 0 ℃; Reflux;

DOI:10.1021/acs.joc.0c01235

Reference yield: 90.0%

1,2,4,5-benzenetetracarboxylic acid (89-05-4) + trimethyl orthoformate (149-73-5) → tetramethyl 1,2,4,5-benzenetetracarboxylate (635-10-9)

Guidance literature:

at 105 - 110 ℃; for 24h; Temperature; Large scale;

upstream raw materials:

methanol

1,2,4,5-benzenetetracarboxylic acid

diazomethane

cyclooctanaphthalene

Downstream raw materials:

1,2,4,5-tetrakis(hydroxymethyl)benzene

tetrakis(2,2,6,6-tetramethyl-1-oxyl-4-piperidyloxy)pyromellitate

cyclohexane-1,2,4,5-tetracarboxylic acid tetramethyl ester

1,2,4,5-cyclohexanetetracarboxylic acid-1,2:4,5-dianhydride

Refernces

• 1、 Lutz, J. Patrick,Davydovich, Oleg,Hannigan, Matthew D.,Moore, Jeffrey S.,Zimmerman, Paul M.,McNeil, Anne J.. "Functionalized and Degradable Polyphthalaldehyde Derivatives". supporting information. p. 14544 - 14548. Retrieved 2019/10/02.
• 2、 -. "Derivative of pyromellitic acid and preparation method of derivative". Paragraph 0030; 0031. . Retrieved 2017/08/30.