1,2,4,5-Cyclohexanetetracarboxylic acid, tetramethyl ester

Base Information

• Chemical Name: 1,2,4,5-Cyclohexanetetracarboxylic acid, tetramethyl ester
• CAS No.: 92298-55-0
• Molecular Formula: C14H20O8
• Molecular Weight: 316.308
• Mol file: 92298-55-0.mol

Synonyms:

Chemical Property of 1,2,4,5-Cyclohexanetetracarboxylic acid, tetramethyl ester

Chemical Property:

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2,4,5-Cyclohexanetetracarboxylic acid, tetramethyl ester

There total 5 articles about 1,2,4,5-Cyclohexanetetracarboxylic acid, tetramethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetramethyl 1,2,4,5-benzenetetracarboxylate (635-10-9) → cyclohexane-1,2,4,5-tetracarboxylic acid tetramethyl ester (92298-55-0)

Guidance literature:

With hydrogen; In methanol; at 180 - 250 ℃; under 37503.8 Torr; Reagent/catalyst; Temperature; Pressure;

Reference yield:

1,2,4,5-benzenetetracarboxylic acid (89-05-4) → cyclohexane-1r,2t,4t,5c-tetracarboxylic acid tetramethyl ester (92298-55-0)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂, aq. Na₂CO₃ / Raney-Ni / 150 °C / 155144 Torr

2: H₂SO₄ / 1,2-dichloro-ethane

With sulfuric acid; hydrogen; sodium carbonate; nickel; In 1,2-dichloro-ethane;

DOI:10.1021/jo01042a009

Reference yield:

methanol (67-56-1) + cyclohexane-1r,2t,4t,5c-tetracarboxylic acid (1147100-49-9) → cyclohexane-1r,2t,4t,5c-tetracarboxylic acid tetramethyl ester (92298-55-0)

Guidance literature:

With sulfuric acid; In 1,2-dichloro-ethane;

DOI:10.1021/jo01042a009

upstream raw materials:

cyclohexane-1e,2a,4a,5e-tetracarboxylic acid

tetramethyl 1,2,4,5-benzenetetracarboxylate

1,2,4,5-benzenetetracarboxylic acid

methanol

Downstream raw materials:

1,2,4,5-cyclohexanetetracarboxylic acid-1,2:4,5-dianhydride