(±)-carbonic acid 2-[4-(3-benzyl-2,4-dioxo-thiazolidin-(5Z)-ylidenemethyl)phenoxymethyl]-2,5,7,8-tetramethylchroman-6-yl tert-butyl ester

Base Information

• Chemical Name: (±)-carbonic acid 2-[4-(3-benzyl-2,4-dioxo-thiazolidin-(5Z)-ylidenemethyl)phenoxymethyl]-2,5,7,8-tetramethylchroman-6-yl tert-butyl ester
• CAS No.: 1448960-17-5
• Molecular Formula: C₃₆H₃₉NO₇S
• Molecular Weight: 629.774
• Mol file: 1448960-17-5.mol

Synonyms:(±)-carbonic acid 2-[4-(3-benzyl-2,4-dioxo-thiazolidin-(5Z)-ylidenemethyl)phenoxymethyl]-2,5,7,8-tetramethylchroman-6-yl tert-butyl ester

Chemical Property of (±)-carbonic acid 2-[4-(3-benzyl-2,4-dioxo-thiazolidin-(5Z)-ylidenemethyl)phenoxymethyl]-2,5,7,8-tetramethylchroman-6-yl tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (±)-carbonic acid 2-[4-(3-benzyl-2,4-dioxo-thiazolidin-(5Z)-ylidenemethyl)phenoxymethyl]-2,5,7,8-tetramethylchroman-6-yl tert-butyl ester

There total 1 articles about (±)-carbonic acid 2-[4-(3-benzyl-2,4-dioxo-thiazolidin-(5Z)-ylidenemethyl)phenoxymethyl]-2,5,7,8-tetramethylchroman-6-yl tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

carbonic acid tert-butyl ester 2-{4-[2,4-dioxo-thiazolidin-(5Z)-ylidenemethyl]phenoxymethyl}-2,5,7,8-tetramethyl-chroman-6-yl ester (1375483-15-0) + benzyl bromide (100-39-0) → (±)-carbonic acid 2-[4-(3-benzyl-2,4-dioxo-thiazolidin-(5Z)-ylidenemethyl)phenoxymethyl]-2,5,7,8-tetramethylchroman-6-yl tert-butyl ester (1448960-17-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 - 80 ℃; Inert atmosphere;

DOI:10.1016/j.ejmech.2014.06.015

Reference yield: 49.0%

(±)-carbonic acid 2-[4-(3-benzyl-2,4-dioxo-thiazolidin-(5Z)-ylidenemethyl)phenoxymethyl]-2,5,7,8-tetramethylchroman-6-yl tert-butyl ester (1448960-17-5) → (±)-3-benzyl-(5Z)-[4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzylidene]thiazolidine-2,4-dione (1448960-16-4)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1016/j.ejmech.2014.06.015

upstream raw materials:

carbonic acid tert-butyl ester 2-{4-[2,4-dioxo-thiazolidin-(5Z)-ylidenemethyl]phenoxymethyl}-2,5,7,8-tetramethyl-chroman-6-yl ester

benzyl bromide

Downstream raw materials:

(±)-3-benzyl-(5Z)-[4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzylidene]thiazolidine-2,4-dione