Chemical Property of Homogentisic acid
Chemical Property:
- Appearance/Colour:off-white to tan crystals or crystalline powder
- Vapor Pressure:1.71E-08mmHg at 25°C
- Melting Point:150-152 °C(lit.)
- Refractive Index:1.5090 (estimate)
- Boiling Point:439.3°Cat760mmHg
- PKA:4.4(at 25℃)
- Flash Point:233.6°C
- PSA：77.76000
- Density:1.478g/cm3
- LogP:0.72490
- Storage Temp.:2-8°C
- Solubility.:Soluble in methanol.
- Water Solubility.:very faint turbidity
- XLogP3:0.5
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:2
- Exact Mass:168.04225873
- Heavy Atom Count:12
- Complexity:168
- Purity/Quality:
-
98% *data from raw suppliers
Homogentisic Acid *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Chemical Classes:Other Classes -> Organic Acids
- Canonical SMILES:C1=CC(=C(C=C1O)CC(=O)O)O
-
Uses
An intermediate in the metabolism of tyrosine and phenylalanine. Occurs in plants and in the urine of alkaptonurics. Homogentisic acid may be used as an analytical reference standard for the quantification of the analyte in the following:Urine matrices using reversed-phase liquid chromatography tandem mass spectrometry (LC-MS/MS).Strawberry tree honey samples using reversed phase-high performance liquid chromatography (RP-HPLC) and ion chromatography (IC).It may also be used as an internal standard for the determination of ascorbic acid (AA) and uric acid (UA) in human plasma samples using high-pressure liquid chromatography–electrochemical detection (HPLC–ECD).
