Technology Process of N,N'-bis<6-(2-tetrahydropyranyloxy)hexyl>-N,N'-di-p-toluenesulfonyl-1,6-hexanediamine
There total 5 articles about N,N'-bis<6-(2-tetrahydropyranyloxy)hexyl>-N,N'-di-p-toluenesulfonyl-1,6-hexanediamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 96 percent / triethylamine, N,N'-dimethylaminopyridine / CH2Cl2 / 3 h / Ambient temperature
2: 1.) NaH / 1.) DMF, 60 deg C, 20 to 25 mm Hg, 30 min 2.) DMF, 60 deg C, 3 h
With
N,N'-dimethylaminopyridine; sodium hydride; triethylamine;
In
dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 70 percent / 48percent aq. HBr / 50 h / 70 °C
2: 95 percent / p-toluenesulfonic acid / diethyl ether / 12 h / Ambient temperature
3: 1.) NaH / 1.) DMF, 60 deg C, 20 to 25 mm Hg, 30 min 2.) DMF, 60 deg C, 3 h
With
hydrogen bromide; sodium hydride; toluene-4-sulfonic acid;
In
diethyl ether;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 95 percent / p-toluenesulfonic acid / diethyl ether / 12 h / Ambient temperature
2: 1.) NaH / 1.) DMF, 60 deg C, 20 to 25 mm Hg, 30 min 2.) DMF, 60 deg C, 3 h
With
sodium hydride; toluene-4-sulfonic acid;
In
diethyl ether;
