Etafenone

Base Information

• Chemical Name: Etafenone
• CAS No.: 90-54-0
• Molecular Formula: C21H27 N O2
• Molecular Weight: 325.451
• European Community (EC) Number: 202-002-9
• UNII: 0I14K589E7
• DSSTox Substance ID: DTXSID6046181
• Nikkaji Number: J4.322B
• Wikipedia: Etafenone
• Wikidata: Q5402380
• NCI Thesaurus Code: C65548
• Metabolomics Workbench ID: 154623
• ChEMBL ID: CHEMBL1736151
• Mol file: 90-54-0.mol

Synonyms:Baxacor;Dialicor;etafenone;etafenone hydrochloride;etaphenone

Chemical Property of Etafenone

Chemical Property:

• Melting Point: <25 °C
• Boiling Point: bp30 264-268°
• PKA: 9.54±0.25(Predicted)
• PSA: 29.54000
• Density: 1.043±0.06 g/cm3(Predicted)
• LogP: 4.22270
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 10
• Exact Mass: 325.204179104
• Heavy Atom Count: 24
• Complexity: 348

Purity/Quality:

99% ^*data from raw suppliers

1-[2-(2-DIETHYLAMINO-ETHOXY)-PHENYL]-3-PHENYL-PROPAN-1-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)CCOC1=CC=CC=C1C(=O)CCC2=CC=CC=C2

Technology Process of Etafenone

There total 2 articles about Etafenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2'-hydroxy-3-phenylpropiophenone (3516-95-8) + 2-(diethylamino)ethyl chloride (100-35-6) → etafenone (90-54-0)

Guidance literature:

Reference yield:

→ etafenone (90-54-0)

Guidance literature:

Reference yield:

etafenone (90-54-0) + benzaldehyde (100-52-7) → 1-(2-Diethylamino-ethoxy)-2-(3-phenyl-2-benzyliden-propionyl)-benzol (96272-01-4)

Guidance literature:

With sodium hydroxide; In ethanol;

upstream raw materials:

2'-hydroxy-3-phenylpropiophenone

2-(diethylamino)ethyl chloride

Downstream raw materials:

1-(2-Diethylamino-ethoxy)-2-(3-phenyl-2-benzyliden-propionyl)-benzol