1,2-Bis(diphenylphosphino)propane

Base Information

• Chemical Name: 1,2-Bis(diphenylphosphino)propane
• CAS No.: 15383-58-1
• Molecular Formula: C27H26 P2
• Molecular Weight: 412.451
• Hs Code.: 2902909090
• DSSTox Substance ID: DTXSID30394560
• Nikkaji Number: J1.226.306F
• ChEMBL ID: CHEMBL69493
• Mol file: 15383-58-1.mol

Synonyms:15383-58-1;1,2-BIS(DIPHENYLPHOSPHINO)PROPANE;1,2-bis-(diphenylphosphino)propane;1-diphenylphosphanylpropan-2-yl(diphenyl)phosphane;Propane-1,2-diylbis(diphenylphosphine);[(2R)-1-diphenylphosphanylpropan-2-yl]-diphenylphosphane;dppip;[(2S)-1-diphenylphosphanylpropan-2-yl]-diphenylphosphane;CHEMBL69493;SCHEMBL613867;DTXSID30394560;WGOBPPNNYVSJTE-UHFFFAOYSA-N;FT-0641151;FT-0771250

Chemical Property of 1,2-Bis(diphenylphosphino)propane

Chemical Property:

• Boiling Point: 521.9±33.0 °C(Predicted)
• PSA: 27.18000
• LogP: 5.64070
• XLogP3: 6.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 7
• Exact Mass: 412.15097482
• Heavy Atom Count: 29
• Complexity: 404

Purity/Quality:

98% ^*data from raw suppliers

1,2-BIS(DIPHENYLPHOSPHINO)PROPANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CP(C1=CC=CC=C1)C2=CC=CC=C2)P(C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 1,2-Bis(diphenylphosphino)propane

There total 4 articles about 1,2-Bis(diphenylphosphino)propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1,2-Dibromopropane (78-75-1) + diphenylphosphane (829-85-6) → 1,2-bis(diphenylphosphino)propane (15383-58-1,67884-33-7)

Guidance literature:

diphenylphosphane; With cesiumhydroxide monohydrate; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Molecular sieve; Inert atmosphere;

1,2-Dibromopropane; In N,N-dimethyl-formamide; at 20 ℃; for 72h; Inert atmosphere; Molecular sieve;

Reference yield:

1,2-propanediene (463-49-0) + diphenylphosphane (829-85-6) → 1,3-bis-(diphenylphosphino)propane (6737-42-4) + 1,2-bis(diphenylphosphino)propane (15383-58-1,67884-33-7) + Diphenylphosphine oxide (4559-70-0) + allyldiphenylphosphine (2741-38-0)

Guidance literature:

for 8h; Irradiation;

DOI:10.1016/0022-328X(91)86141-C

Reference yield:

1,2-propanediol bismesylate (26439-20-3) + lithium diphenylphosphide (65567-06-8,4541-02-0) → 1,2-bis(diphenylphosphino)propane (15383-58-1,67884-33-7)

Guidance literature:

In tetrahydrofuran; at -78 - 20 ℃; Schlenk technique;

DOI:10.1021/cs400651h

upstream raw materials:

1,2-propanediene

diphenylphosphane

1,2-Dibromopropane

1,2-propanediol bismesylate

Downstream raw materials:

[Pd(NO₂)2((C₆H₅)2P)2(CH₂)3]

[Pd(NO₂)2((C₆H₅)2P)2(CH₂)3]

cobalt[1,3-bis(diphenylphosphino)propane] dibromide

cis[PtPh₂(1,2-bis(diphenylphosphanyl)propane)]

Refernces

• 1、 -. "ETHYLENE TETRAMERIZATION CATALYST SYSTEMS AND METHOD FOR PREPARING 1-OCTENE USING THE SAME". Page/Page column 13. . Retrieved 2010/06/16.
• 2、 Mitchell, Terence N.,Heesche, Kerstin. "Preparation of vinylphosphines by means of free radical addition of diphenylphosphine to alkynes and allenes". . p. 163 - 170. Retrieved 2007/10/02.