methyl 2-(4-hydroxy-2,6-dimethoxyphenoxy)-4-methoxy-6-methylbenzoate

Base Information

• Chemical Name: methyl 2-(4-hydroxy-2,6-dimethoxyphenoxy)-4-methoxy-6-methylbenzoate
• CAS No.: 81574-62-1
• Molecular Formula: C₁₈H₂₀O₇
• Molecular Weight: 348.353
• Mol file: 81574-62-1.mol

Synonyms:methyl 2-(4-hydroxy-2,6-dimethoxyphenoxy)-4-methoxy-6-methylbenzoate

Chemical Property of methyl 2-(4-hydroxy-2,6-dimethoxyphenoxy)-4-methoxy-6-methylbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-(4-hydroxy-2,6-dimethoxyphenoxy)-4-methoxy-6-methylbenzoate

There total 3 articles about methyl 2-(4-hydroxy-2,6-dimethoxyphenoxy)-4-methoxy-6-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

sodium methylate (124-41-4) + 2',6,6'-trimethoxy-4-methylspiro-3(2H),4'-dione (74628-35-6) → methyl 2-(4-hydroxy-2,6-dimethoxyphenoxy)-4-methoxy-6-methylbenzoate (81574-62-1)

Guidance literature:

In methanol; for 1h; Heating;

Reference yield:

2,4'-dihydroxy-2',4,6'-trimethoxy-6-methylbenzophenone (74628-36-7) → methyl 2-(4-hydroxy-2,6-dimethoxyphenoxy)-4-methoxy-6-methylbenzoate (81574-62-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 47 mg / potassium carbonate, potassium hexacyanoferrate(III) / dioxane; H₂O / 0.5 h

2: 86 percent / methanol / 1 h / Heating

With potassium carbonate; potassium hexacyanoferrate(III); In 1,4-dioxane; methanol; water;

Reference yield:

2',6,6'-trimethoxy-4-methylspiro-3(2H),4'-dione (74628-35-6) → methyl 2-(4-hydroxy-2,6-dimethoxyphenoxy)-4-methoxy-6-methylbenzoate (81574-62-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 620 mg / zinc, glacial acetic acid / 1 h

2: 47 mg / potassium carbonate, potassium hexacyanoferrate(III) / dioxane; H₂O / 0.5 h

3: 86 percent / methanol / 1 h / Heating

With potassium carbonate; acetic acid; potassium hexacyanoferrate(III); zinc; In 1,4-dioxane; methanol; water;

upstream raw materials:

sodium methylate

2',6,6'-trimethoxy-4-methylspiro-3(2H),4'-dione

2,4'-dihydroxy-2',4,6'-trimethoxy-6-methylbenzophenone

Downstream raw materials:

2-hydroxy-2',4,4'6'-tetramethoxy-6-methylbenzophenone

2,4'-dihydroxy-2',4,6'-trimethoxy-6-methylbenzophenone

1,3,6-trimethoxy-8-methyl-9H-xanthen-9-one

lichenxanthone