2-Bromo-1-(2-methyl-3-nitrophenyl)ethanone

Base Information

Chemical Name:2-Bromo-1-(2-methyl-3-nitrophenyl)ethanone
CAS No.:75473-12-0
Molecular Formula:C₉H₈BrNO₃
Molecular Weight:258.071
Hs Code.:
DSSTox Substance ID:DTXSID101268896

Synonyms:2-Bromo-1-(2-methyl-3-nitrophenyl)ethanone;SCHEMBL23554226;DTXSID101268896;AKOS018708931;75473-12-0

Suppliers and Price of 2-Bromo-1-(2-methyl-3-nitrophenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Bromo-1-(2-methyl-3-nitrophenyl)ethanone

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:256.96876
Heavy Atom Count:14
Complexity:239

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=CC=C1[N+](=O)[O-])C(=O)CBr

Technology Process of 2-Bromo-1-(2-methyl-3-nitrophenyl)ethanone

There total 4 articles about 2-Bromo-1-(2-methyl-3-nitrophenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 75473-11-9
1-(2-methyl-3-nitro-phenyl)ethanone

: 75473-12-0
ω-Brom-2-methyl-3-nitro-acetophenon

Guidance literature:: With aluminium trichloride; bromine; In chloroform; at 50 ℃; for 0.25h;
DOI:10.1002/ardp.19803130704

Reference yield:

: 39053-41-3
2-methyl-3-nitrobenzoyl chloride

: 75473-12-0
ω-Brom-2-methyl-3-nitro-acetophenon

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) Mg, CCl₄ / 1.) EtOH, ether, reflux, 3 h, 2.) EtOH, ether, reflux, 10 min.

2: conc. H₂SO₄ / aq. acetic acid / 4 h / Heating

3: 99 percent / AlCl₃, Br₂ / CHCl₃ / 0.25 h / 50 °C

With tetrachloromethane; aluminium trichloride; sulfuric acid; bromine; magnesium; In chloroform; acetic acid;
DOI:10.1002/ardp.19803130704

Reference yield:

: 120100-32-5
diethyl 2-(2-methyl-3-nitrobenzoyl)malonate

: 75473-12-0
ω-Brom-2-methyl-3-nitro-acetophenon

Guidance literature:: Multi-step reaction with 2 steps

1: conc. H₂SO₄ / aq. acetic acid / 4 h / Heating

2: 99 percent / AlCl₃, Br₂ / CHCl₃ / 0.25 h / 50 °C

With aluminium trichloride; sulfuric acid; bromine; In chloroform; acetic acid;
DOI:10.1002/ardp.19803130704