Trimethyl-[phenylsulfanyl-(2,4,6-tri-tert-butyl-phenyl)-methyl]-silane

Base Information

• Chemical Name: Trimethyl-[phenylsulfanyl-(2,4,6-tri-tert-butyl-phenyl)-methyl]-silane
• CAS No.: 121654-27-1
• Molecular Formula: C₂₈H₄₄SSi
• Molecular Weight: 440.809
• Mol file: 121654-27-1.mol

Synonyms:Trimethyl-[phenylsulfanyl-(2,4,6-tri-tert-butyl-phenyl)-methyl]-silane

Chemical Property of Trimethyl-[phenylsulfanyl-(2,4,6-tri-tert-butyl-phenyl)-methyl]-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Trimethyl-[phenylsulfanyl-(2,4,6-tri-tert-butyl-phenyl)-methyl]-silane

There total 2 articles about Trimethyl-[phenylsulfanyl-(2,4,6-tri-tert-butyl-phenyl)-methyl]-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,6-tri-(tert-butyl)thiobenzaldehyde (84543-57-7) → Trimethyl-[phenylsulfanyl-(2,4,6-tri-tert-butyl-phenyl)-methyl]-silane (121654-27-1)

Guidance literature:

Multi-step reaction with 2 steps

2: 1) BuLi / 2) Pd(PPh₃)4

With n-butyllithium; tetrakis(triphenylphosphine) palladium⁽⁰⁾;

Reference yield:

iodobenzene (591-50-4) + (2,4,6-Tri-tert-butyl-phenyl)-trimethylsilanyl-methanethiol (121654-26-0) → Trimethyl-[phenylsulfanyl-(2,4,6-tri-tert-butyl-phenyl)-methyl]-silane (121654-27-1)

Guidance literature:

With n-butyllithium; tetrakis(triphenylphosphine) palladium⁽⁰⁾; Yield given. Multistep reaction; 1.) THF, -78 deg C; 2.) benzene, reflux, 3 h;

DOI:10.1021/ja00197a070

Reference yield:

Trimethyl-[phenylsulfanyl-(2,4,6-tri-tert-butyl-phenyl)-methyl]-silane (121654-27-1) → 2,2-Dimethyl-1-(2,4,6-tri-tert-butyl-phenyl)-propane-1-selenol (121654-31-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 1) LiNaph, 2) CuCN

2: 44 percent / n-Bu₄NF / CH₂Cl₂ / -25 °C

3: 26 percent

With tetrabutyl ammonium fluoride; lithium 1-naphthalenide; In dichloromethane;

upstream raw materials:

iodobenzene

(2,4,6-Tri-tert-butyl-phenyl)-trimethylsilanyl-methanethiol

2,4,6-tri-(tert-butyl)thiobenzaldehyde

Downstream raw materials:

Trimethyl-[selenocyanato-(2,4,6-tri-tert-butyl-phenyl)-methyl]-silane

2,4,6-Tri-tert-butylselenobenzaldehyde

Butyl-[1-(2,4,6-tri-tert-butyl-phenyl)-meth-(E)-ylidene]-amine

2,2-Dimethyl-1-(2,4,6-tri-tert-butyl-phenyl)-propane-1-selenol