1-Hydroxymethyl-1-methyl-tetralin

Base Information

Chemical Name:1-Hydroxymethyl-1-methyl-tetralin
CAS No.:25634-94-0
Molecular Formula:C₁₂H₁₆O
Molecular Weight:176.258
Hs Code.:
European Community (EC) Number:829-384-5
ChEMBL ID:CHEMBL2041409

Synonyms:25634-94-0;1-Hydroxymethyl-1-methyl-tetralin;(1-methyl-1,2,3,4-tetrahydronaphthalen-1-yl)methanol;(1-methyl-3,4-dihydro-2H-naphthalen-1-yl)methanol;starbld0010603;CHEMBL2041409;SCHEMBL20136561;AKOS015402912;EN300-2559475

Suppliers and Price of 1-Hydroxymethyl-1-methyl-tetralin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Hydroxymethyl-1-methyl-tetralin

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:176.120115130
Heavy Atom Count:13
Complexity:178

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(CCCC2=CC=CC=C21)CO

Technology Process of 1-Hydroxymethyl-1-methyl-tetralin

There total 9 articles about 1-Hydroxymethyl-1-methyl-tetralin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1914-65-4
tetralin-1-carboxylic acid

: 25634-94-0
(1-methyl-1,2,3,4-tetrahydronaphthalen-1-yl)methanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: toluene-4-sulfonic acid / 5 h / Inert atmosphere; Reflux

2.1: lithium diisopropyl amide / tetrahydrofuran / 0.67 h / 0 - 20 °C / Inert atmosphere

2.2: 16 h / 0 - 20 °C / Inert atmosphere

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 5 h / 0 - 20 °C / Inert atmosphere

With lithium aluminium tetrahydride; toluene-4-sulfonic acid; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1021/acs.jmedchem.5b00393

Reference yield:

: 1914-65-4
tetralin-1-carboxylic acid

: 25634-94-0
(1-methyl-1,2,3,4-tetrahydronaphthalen-1-yl)methanol

: 66377-63-7
(1,2,3,4-tetrahydronaphthalen-4-yl)methanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: diethyl ether

2.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C

2.2: -78 - 0 °C

3.1: lithium aluminium tetrahydride / diethyl ether / 0 °C

With lithium aluminium tetrahydride; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether;
DOI:10.1016/j.bmcl.2012.05.022