3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione

Base Information

Chemical Name:3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione
CAS No.:1312991-15-3
Molecular Formula:C₂₃H₂₅F₆N₃O₂
Molecular Weight:489.461
Hs Code.:
Mol file:1312991-15-3.mol

Synonyms:quinine

Suppliers and Price of 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Strem Chemicals
3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee) (99% ee)
100mg
$ 109.00

ChemScene
3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]amino]-3-cyclobutene-1,2-dione 97.25%
100mg
$ 145.00

Total 4 raw suppliers

Chemical Property of 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee) (99% ee) ^*data from reagent suppliers

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Pictogram(s):
Hazard Codes:

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Technology Process of 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione

There total 3 articles about 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 824938-80-9,824938-98-9
(1S, 2S)-trans-2-(1-piperidinyl)cyclohexylamine

: 1223105-85-8
3-(3,5-ditrifluoromethylphenylamino)-4-methoxybutane-3-en-1,2-dione

: 1312991-15-3
quinine

Guidance literature:: In dichloromethane; at 20 ℃; for 24h;
DOI:10.1002/adsc.201000981

Reference yield:

: 21436-03-3
(S,S)-1,2-diaminocyclohexane

: 1312991-15-3
quinine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tris(acetoxy)borohydride / water; 1,2-dichloro-ethane / 3 h / 20 °C

2: dichloromethane / 24 h / 20 °C

With sodium tris(acetoxy)borohydride; In dichloromethane; water; 1,2-dichloro-ethane;
DOI:10.1002/adsc.201000981

Reference yield:

: 111-30-8,29257-65-6,79215-57-9
Glutaraldehyde

: 1312991-15-3
quinine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tris(acetoxy)borohydride / water; 1,2-dichloro-ethane / 3 h / 20 °C

2: dichloromethane / 24 h / 20 °C

With sodium tris(acetoxy)borohydride; In dichloromethane; water; 1,2-dichloro-ethane;
DOI:10.1002/adsc.201000981