(S)-4-Benzyl-3-(2-benzyloxy-acetyl)-1-phenyl-imidazolidin-2-one

Base Information

• Chemical Name: (S)-4-Benzyl-3-(2-benzyloxy-acetyl)-1-phenyl-imidazolidin-2-one
• CAS No.: 158724-93-7
• Molecular Formula: C₂₅H₂₄N₂O₃
• Molecular Weight: 400.477
• Mol file: 158724-93-7.mol

Synonyms:(S)-4-Benzyl-3-(2-benzyloxy-acetyl)-1-phenyl-imidazolidin-2-one

Chemical Property of (S)-4-Benzyl-3-(2-benzyloxy-acetyl)-1-phenyl-imidazolidin-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-4-Benzyl-3-(2-benzyloxy-acetyl)-1-phenyl-imidazolidin-2-one

There total 1 articles about (S)-4-Benzyl-3-(2-benzyloxy-acetyl)-1-phenyl-imidazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

Benzyloxyacetyl chloride (19810-31-2) + (4S)-1-phenyl-4-phenylmethyl-2-imidazolidinone (195198-33-5) → (S)-4-Benzyl-3-(2-benzyloxy-acetyl)-1-phenyl-imidazolidin-2-one (158724-93-7)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; for 1h;

DOI:10.1016/j.tetasy.2005.07.036

Reference yield: 85.0%

allyl iodid (556-56-9) + (S)-4-Benzyl-3-(2-benzyloxy-acetyl)-1-phenyl-imidazolidin-2-one (158724-93-7) → (S)-4-Benzyl-3-((R)-2-benzyloxy-pent-4-enoyl)-1-phenyl-imidazolidin-2-one

Guidance literature:

(S)-4-Benzyl-3-(2-benzyloxy-acetyl)-1-phenyl-imidazolidin-2-one; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1h;

allyl iodid; In tetrahydrofuran; at -78 - -40 ℃;

DOI:10.1016/j.tetasy.2005.07.036

Reference yield: 82.0%

benzyl bromide (100-39-0) + (S)-4-Benzyl-3-(2-benzyloxy-acetyl)-1-phenyl-imidazolidin-2-one (158724-93-7) → (S)-4-Benzyl-3-((R)-2-benzyloxy-3-phenyl-propionyl)-1-phenyl-imidazolidin-2-one

Guidance literature:

(S)-4-Benzyl-3-(2-benzyloxy-acetyl)-1-phenyl-imidazolidin-2-one; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1h;

benzyl bromide; In tetrahydrofuran; at -78 - -40 ℃;

DOI:10.1016/j.tetasy.2005.07.036

upstream raw materials:

Benzyloxyacetyl chloride

(4S)-1-phenyl-4-phenylmethyl-2-imidazolidinone