N-hydroxy-1-[3-(methoxymethyl)phenyl]-1-(1-methyl-1H-tetrazol-5-yl)methanimine

Base Information

• Chemical Name: N-hydroxy-1-[3-(methoxymethyl)phenyl]-1-(1-methyl-1H-tetrazol-5-yl)methanimine
• CAS No.: 1203575-92-1
• Molecular Formula: C₁₁H₁₃N₅O₂
• Molecular Weight: 247.257
• Mol file: 1203575-92-1.mol

Synonyms:N-hydroxy-1-[3-(methoxymethyl)phenyl]-1-(1-methyl-1H-tetrazol-5-yl)methanimine

Chemical Property of N-hydroxy-1-[3-(methoxymethyl)phenyl]-1-(1-methyl-1H-tetrazol-5-yl)methanimine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-hydroxy-1-[3-(methoxymethyl)phenyl]-1-(1-methyl-1H-tetrazol-5-yl)methanimine

There total 1 articles about N-hydroxy-1-[3-(methoxymethyl)phenyl]-1-(1-methyl-1H-tetrazol-5-yl)methanimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

[3-(methoxymethyl)phenyl](1-methyl-1H-tetrazol-5-yl)methanone (1203575-91-0) → N-hydroxy-1-[3-(methoxymethyl)phenyl]-1-(1-methyl-1H-tetrazol-5-yl)methanimine (1203575-92-1)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; at 70 ℃; for 4h;

Reference yield: 47.0%

N-hydroxy-1-[3-(methoxymethyl)phenyl]-1-(1-methyl-1H-tetrazol-5-yl)methanimine (1203575-92-1) + tert-butyl 6-(hydroxymethyl)-2-pyridinylcarbamate (203321-83-9) → tert-butyl (6-{[({[3-(methoxymethyl)phenyl](1-methyl-1H-tetrazol-5-yl)methylene}amino)oxy]methyl}pyridin-2-yl)carbamate (1203575-69-2)

Guidance literature:

tert-butyl 6-(hydroxymethyl)-2-pyridinylcarbamate; With methanesulfonyl chloride; triethylamine; In dichloromethane; at 0 - 20 ℃;

N-hydroxy-1-[3-(methoxymethyl)phenyl]-1-(1-methyl-1H-tetrazol-5-yl)methanimine; With caesium carbonate; potassium iodide; In dichloromethane; acetonitrile; at 20 ℃; for 24h;

upstream raw materials:

[3-(methoxymethyl)phenyl](1-methyl-1H-tetrazol-5-yl)methanone

Downstream raw materials:

tert-butyl (6-{[({[3-(methoxymethyl)phenyl](1-methyl-1H-tetrazol-5-yl)methylene}amino)oxy]methyl}pyridin-2-yl)carbamate