Technology Process of C25H20ClN3O3S
There total 8 articles about C25H20ClN3O3S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-(1,1-dioxo-1λ6-isothiazolidin-2-yl)benzoic acid;
With
HATU;
In
N,N-dimethyl-formamide;
for 0.0833333h;
4-chloro-3-(1,6-naphthyridin-5-yl)aniline;
In
N,N-dimethyl-formamide;
at 20 ℃;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: trifluoroacetic acid / dichloromethane / 15 h / 20 °C
2.1: HATU / N,N-dimethyl-formamide / 0.08 h
2.2: 20 °C / Inert atmosphere
With
HATU; trifluoroacetic acid;
In
dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: pyridine / 1 h / 20 °C
2.1: tetra-(n-butyl)ammonium iodide; sodium hydroxide / water; tetrahydrofuran / 22 h / 20 °C
3.1: trifluoroacetic acid / dichloromethane / 15 h / 20 °C
4.1: HATU / N,N-dimethyl-formamide / 0.08 h
4.2: 20 °C / Inert atmosphere
With
pyridine; tetra-(n-butyl)ammonium iodide; HATU; trifluoroacetic acid; sodium hydroxide;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;